Fundraising Fox

Optimeos

Princeton, US · Founded 2018 · 10 employees on LinkedIn · 3 known investors

Find your way into Optimeos

668 people in our graph share verified history with the Optimeos team — schools, employers, funds. One of them is your warm intro.

Teresa Chanunlockedknows Gregory Harriman · together at Johnson & Johnson (overlapped)
×2knows the team · via Princeton University
×2knows the team · via UC San Diego
×6knows the team · via Middlebury College
knows the team · via Baylor College of Medicine

Optimeos develops a nanoparticle-based drug formulation and delivery platform (CINCs and LINCs) for complex biologics including mRNA, DNA, peptides, and proteins, targeting rare diseases, immunology, and metabolic conditions such as obesity. Its technology enables intracellular and long-acting delivery for pharmaceutical and biotech partners addressing challenges like tissue targeting and dosing profiles.

Founders & leadership

Optimeos was founded in 2018 by Robert K. Prud'homme, PhD, Bob Prud'homme, Rob Pagels, and Chet Markwalter.

RK
Robert K. Prud'homme, PhDCo-founder
BPBob Prud'homme
Bob Prud'hommeLeadership (PhD)
RPRob Pagels
Rob PagelsLeadership (PhD)
CMChet Markwalter
Chet MarkwalterinLeadership (PhD)
SH
Shahram Hejazi, PhDinFounder and CEO2019–2026Investor at Third Rock Ventures
SH
Shahram HejaziinLeadership (PhD)Investor at Third Rock Ventures
GHGregory Harriman
Gregory HarrimaninLeadership (MD)Partner at BioAdvance
MEMark Esposito
Mark EspositoinLeadership (PhD)

Board

JS
Jason SmithLeadership (PhD)
BD
Benjamin DoranzBoard director
JS
Jason Smith, PhDBoard director

Investors · 3

Reported raises · per SEC filings

Form D private placements

$4.4M disclosed across 4 rounds · 2020–2026

$1MraisedJun 2026 · 1 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Jason SmithDirector
  • Shahram HejaziExecutive Officer, Director
  • Robert K Prud'hommeDirector
  • Benjamin DoranzDirector
Offering amount
$2M
Amount sold
$1M
First sale
May 2026
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$2.9MraisedNov 2024 · 5 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Benjamin DoranzDirector
  • Shahram Hejazi, PhDExecutive Officer, Director
  • Jason Smith, PhDDirector
  • Robert K. Prud'homme, PhDDirector
Offering amount
$5M
Amount sold
$2.9M
First sale
Jun 2023
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$175KraisedJun 2021 · 4 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Jason Smith, PhDDirector
  • Robert K Prud'homme, PhDDirector
  • Shahram Hejazi, PhDExecutive Officer, Director
Offering amount
$300K
Amount sold
$175K
First sale
May 2021
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$270KraisedAug 2020 · 3 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Robert Prud'homme, PhDDirector
  • Jason Smith, PhDDirector
  • Shahram Hejazi, PhDExecutive Officer, Director
Offering amount
$400K
Amount sold
$270K
First sale
Aug 2020
Incorporated
Corporation, Delaware, 2016
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Founder mafia

2 people who came through Optimeos went on to found or lead other companies.

Non-dilutive funding · 5 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
National Science FoundationPhase II2023$1M
National Institutes of Health (NIH)National Institutes of HealthPhase I2022$287.7K
National Science FoundationPhase ISTTR2021$256K
National Institutes of Health (NIH)National Institutes of HealthPhase I2021$255.4K
National Science FoundationPhase ISTTR2019$225K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Frequently asked questions

What does Optimeos do?
Optimeos develops a nanoparticle-based drug formulation and delivery platform (CINCs and LINCs) for complex biologics including mRNA, DNA, peptides, and proteins, targeting rare diseases, immunology, and metabolic conditions such as obesity. Its technology enables intracellular and long-acting delivery for pharmaceutical and biotech partners addressing challenges like tissue targeting and dosing profiles.
Who founded Optimeos?
Optimeos was founded by Robert K. Prud'homme, PhD, Bob Prud'homme, Rob Pagels, Chet Markwalter in 2018.
Who are Optimeos's investors?
Optimeos's investors include 7G BioVentures, Anzu Partners, Hatch BioFund.
How much funding has Optimeos raised?
Optimeos has disclosed $4.4M raised across 4 rounds.
Where is Optimeos headquartered?
Optimeos is headquartered in Princeton, US.