MantleBio
DefunctYC S23Founded 2023 · 7 employees · 4 known investors
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964 people in our graph share verified history with the MantleBio team — schools, employers, funds. One of them is your warm intro.
Anika Guptaunlockedknows Emily Damato · together at Broad Institute (overlapped)
×4knows the team · via Broad Institute
×2knows the team · via Google
knows the team · via Massachusetts Institute of Technology
×4knows the team · via Y Combinator
MantleBio provides a data management and analytics platform designed for biotech researchers and scientific teams. The platform integrates biological data, enables advanced bioinformatics analysis, and accelerates drug development and genomics research workflows.
Also known as DryBox Bio
Founders & leadership· Y Combinator alumni (S23)
MantleBio was founded in 2023 by Emily Damato and Madeline Schade.
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Emily Damatoin𝕏CEO, Co-Founder2023–2025She previously held software development roles at GRAIL, Arsenal Bio, and The Broad Institute, and holds degrees in computer science and biology from MIT.
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Madeline Schadein𝕏CTO, Co-Founder2023–2025She previously held software engineering roles at Google, Arsenal Bio, and GRAIL.
Investors · 4
Competitors · 6
by search overlapManifold7 shared keywordsManifold Bio combines AI-guided protein design with high-throughput in vivo screening to engineer tissue-targeted biologics and deliver therapeutic payloads to specific organs. The company develops a computational and experimental platform to optimize pharmacokinetics and biodistribution directly in living systems for drug discovery and development.
Mantle5 shared keywordsMantle provides AI-based automation for institutional investors such as state investment boards, collecting documents from email and investor portals and extracting data like capital calls, NAVs, and K-1s into auditable, source-linked records. Its tools support portfolio analytics, cash management, faster quarter-close reporting, and querying quarterly reports for cited answers.
Mammoth Biosciences5 shared keywordsMammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.
Mustang Bio5 shared keywordsMustang Bio in-licenses and develops next-generation therapies aimed at treating patients, operating in the biotechnology and therapeutics sector.
Talus Bio5 shared keywordsTalus develops a proprietary platform that measures and modulates the regulome—the body's gene expression control system—in native cellular contexts. The company designs AI-driven compounds and uses functional proteomics to enable drug discovery for transcription factors and regulatory proteins implicated in oncology, rare disease, and immune dysfunction.
Mantle4 shared keywordsMantle operates an Ethereum layer-2 network using ZK proofs, along with a treasury and token-holder governed roadmap for on-chain products. It also runs the Mantle EcoFund, a $200M capital pool that backs projects in its ecosystem, with support from Mirana Ventures and Bybit for liquidity and DeFi-CeFi interoperability.
Companies competing with MantleBio for the same Google search keywords, organic and paid, via search-intersection analysis.
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Frequently asked questions
- What does MantleBio do?
- MantleBio provides a data management and analytics platform designed for biotech researchers and scientific teams. The platform integrates biological data, enables advanced bioinformatics analysis, and accelerates drug development and genomics research workflows.
- Who founded MantleBio?
- MantleBio was founded by Emily Damato, Madeline Schade in 2023.
- Who are MantleBio's investors?
- MantleBio's investors include Hawk Hill Ventures, Lobster Capital, The E14 Fund, Y Combinator.









