Macromoltek
YC W18Austin, US · Founded 2010 · 14 employees · 2 known investors
Macromoltek provides computational modeling and AI-driven antibody design services to biotech and pharmaceutical companies, accelerating the discovery and optimization of therapeutic antibodies. The platform reduces time-to-market and increases the probability of clinical success in drug development.
AI & Machine LearningBiotechHealthtechAI-powered Drug DiscoveryDeep LearningTherapeuticsUnited States of AmericaAmerica / Canada
Founders & leadership· Y Combinator alumni (W18)
Macromoltek was founded in 2010 by Monica Berrondo and Susana Kaufmann.
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Monica Berrondoin𝕏Founder/CEOMonica Berrondo holds a Ph.D. and brings combined expertise in computational biology, antibody structure prediction, and protein analysis to Macromoltek.
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Susana KaufmanninFounder/CTOShe has over 25 years of software development experience across petrochemical, combustive engineering, pharmaceutical, and financial industries, with expertise in cross-platform development and computer simulation.
Investors · 2
Competitors · 4
by search overlapMolecular Devices6 shared keywordsMolecular Devices provides automated systems and services to support 3D cell biology research workflows, including cell culture automation, organoid expansion services, and imaging analysis tools for drug discovery and preclinical research.
Aro Biotherapeutics3 shared keywordsAro Biotherapeutics develops tissue-targeted genetic medicines using a proprietary protein technology called Centyrins. The company builds a wholly-owned pipeline of Centyrin-based therapeutic candidates and partners with industry to enable tissue-specific targeting of therapeutics across a range of diseases.
Manifold3 shared keywordsManifold Bio combines AI-guided protein design with high-throughput in vivo screening to engineer tissue-targeted biologics and deliver therapeutic payloads to specific organs. The company develops a computational and experimental platform to optimize pharmacokinetics and biodistribution directly in living systems for drug discovery and development.
Mtem3 shared keywordsMolecular Templates, Inc. was a clinical-stage biopharmaceutical company formerly based in Austin, TX. The company is no longer operating.
Companies competing with Macromoltek for the same Google search keywords, organic and paid, via search-intersection analysis.
Non-dilutive funding · 2 SBIR/STTR awards
Federal grants — no equity taken| Agency | Phase | Year | Amount |
|---|---|---|---|
| National Science Foundation | Phase II | 2016 | $750K |
| National Science Foundation | Phase I | 2015 | $150K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.
Frequently asked questions
- What does Macromoltek do?
- Macromoltek provides computational modeling and AI-driven antibody design services to biotech and pharmaceutical companies, accelerating the discovery and optimization of therapeutic antibodies. The platform reduces time-to-market and increases the probability of clinical success in drug development.
- Who founded Macromoltek?
- Macromoltek was founded by Monica Berrondo, Susana Kaufmann in 2010.
- Who are Macromoltek's investors?
- Macromoltek's investors include Y Combinator, DCVC (Data Collective).
- Where is Macromoltek headquartered?
- Macromoltek is headquartered in Austin, US.


