Cybele Microbiome
San Diego, US · Delaware corporation · 6 employees on LinkedIn · 1 known investors
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Cybele Microbiome studies how skincare ingredients affect the skin microbiome and its postbiotic output, using that knowledge in clinical trials to develop products with better efficacy and fewer side effects. It focuses on the link between ingredients, the microbiome, and human skin health.
Also known as Cybele
Founders & leadership
Investors · 1
Reported raises · per SEC filings
Form D private placements$1.6M disclosed across 4 rounds · 2018–2024
▶$252KraisedMar 2024 · 5 investors · BiotechnologyRule 506(b)
- Nicole M. ScottExecutive Officer, Director
- Offering amount
- $500K
- Amount sold
- $252K
- First sale
- Feb 2024
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$877raisedFeb 2023 · 19 investors · BiotechnologyRule 506(b)
- Nicole M. ScottExecutive Officer, Director
- Offering amount
- $877
- Amount sold
- $877
- First sale
- Dec 2018
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$500KraisedNov 2022 · 1 investors · BiotechnologyRule 506(b)
- Nicole M. ScottExecutive Officer, Director
- Offering amount
- $1M
- Amount sold
- $500K
- First sale
- Nov 2022
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$893.5KraisedNov 2022 · 19 investors · BiotechnologyRule 506(b)
- Nicole M. ScottExecutive Officer, Director
- Offering amount
- $893.5K
- Amount sold
- $893.5K
- First sale
- Oct 2018
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Company profile
researched Aug 2026Cybele Microbiome is a San Diego-based company focused on the relationship between skincare ingredients, the skin microbiome, and skin health. Its stated premise is that every ingredient applied to skin affects both the skin itself and the resident microbial community, and that the microbiome should be treated as an active ingredient rather than a target for elimination.
The company's technology characterizes how ingredients change microbiome composition and the downstream effects on the postbiotic output of the microbiome. It applies these findings in clinical trials with the aim of demonstrating improved efficacy and reduced side effects for skincare formulations. The company also states that it works with outside scientists as partners.
Latest developments
In March 2023 the company announced the launch of Rulo Skin Health. It was previously a finalist at CES 2022 in the Procter & Gamble Venture Challenge, and founder Nicole Scott presented at the Microbiome and Probiotics Virtual Conference.
▸Full profile — technology, go-to-market, geography
Technology
The company's approach centers on assessing the effect of topical ingredients on skin microbiome composition and on the resulting postbiotic output of that microbiome, then combining those measurements with clinical trials to evaluate efficacy and side effects.
Go-to-market
The company positions its work around skincare ingredients and formulations, and states that scientists partner with it.
Geography
Headquartered in San Diego, United States.
Compiled by commissioned research from 1 cited public sources — announcements, filings, and press listed under research sources below.
Non-dilutive funding · 1 SBIR/STTR award
Federal grants — no equity taken| Agency | Phase | Year | Amount |
|---|---|---|---|
| National Science Foundation | Phase I | 2019 | $225K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.
Timeline · 3
launches, deals, and filingsNicole Scott presented at the Microbiome and Probiotics Virtual Conference.
The company was named a finalist at CES 2022 for the Procter & Gamble Venture Challenge.
Dated company events from announcements, filings, and press; legal rows summarize public dockets and regulator releases.
Legal entities · 1
corporate structureIn the news
▸Research sources · 1
primary sources listed
- Cybele Microbiomecybelemicrobiome.com · web
1 public sources were cited for this profile; the first-party ones are listed here.
Frequently asked questions
- What does Cybele Microbiome do?
- San Diego company researching how skincare ingredients affect the skin microbiome and its postbiotic output.
- Who founded Cybele Microbiome?
- Cybele Microbiome was founded by Nicole Scott.
- Who are Cybele Microbiome's investors?
- Cybele Microbiome's investors include Evolution VC Partners.
- How much funding has Cybele Microbiome raised?
- Cybele Microbiome has disclosed $1.6M raised across 4 rounds.
- Where is Cybele Microbiome headquartered?
- Cybele Microbiome is headquartered in San Diego, US.