Fundraising Fox

Clerio Vision

Rochester, US · Founded 2014 · 39 employees on LinkedIn · 3 known investors

Clerio Vision is a development-stage medical device company developing LIRIC, a femtosecond laser technology that changes the refractive index of lens materials or corneal tissue without cutting or removing tissue. It applies this platform across four ophthalmic areas—multifocal contact lenses, myopia control lenses, post-implant intraocular lens adjustment, and incisionless laser vision correction—for patients with presbyopia, myopia, and other refractive errors.

Also known as Clerio

Founders & leadership

AZAlex Zapesochny
Alex ZapesochnyCEO
ASAlissa Seidman
Alissa SeidmanCFO
LZLen Zheleznyak
Len ZheleznyakChief Scientific Officer
WKWayne Knox
Wayne KnoxChief Research Officer
AL
Alexandra LatypovaNamed on SEC filing

Board

DW
David WilliamsBoard director
BMBrian Model
Brian ModelBoard director
ACArunas Chesonis
Arunas ChesonisBoard director
JMJ. Mikael Totterman
J. Mikael TottermanChairman

Investors · 3

Reported raises · per SEC filings

Form D private placements

$28.9M disclosed across 5 rounds · 2014–2020

$8.3MraisedJan 2021 · 45 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Brian ModelDirector
  • David WilliamsDirector
  • Arunas ChesonisDirector
  • Alex ZapesochnyExecutive Officer, Director, Promoter
  • Alexandra LatypovaExecutive Officer, Director, Promoter
  • J. Mikael TottermanExecutive Officer, Director, Promoter
  • Robert CochraneDirector
Offering amount
$12.5M
Amount sold
$8.3M
Minimum investment
$30K
First sale
Dec 2020
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$11.9MraisedJul 2019 · 9 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Arunas ChesonisDirector
  • Brian ModelDirector
  • Alexandra LatypovaExecutive Officer, Director, Promoter
  • Alex ZapesochnyExecutive Officer, Director, Promoter
  • J. Mikael TottermanExecutive Officer, Director, Promoter
  • David WilliamsDirector
Offering amount
$25M
Amount sold
$11.9M
Minimum investment
$100K
First sale
Jun 2019
Incorporated
Corporation, Delaware, 2014
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$3.6MraisedJul 2017 · 33 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • J. Mikael TottermanExecutive Officer, Promoter
  • David WilliamsDirector
  • Alex ZapesochnyExecutive Officer, Director, Promoter
  • Arunas ChesonisDirector
  • Alexandra LatypovaExecutive Officer, Director, Promoter
  • Brian ModelDirector
Offering amount
$5M
Amount sold
$3.6M
Minimum investment
$3.1K
First sale
Jul 2017
Incorporated
Corporation, Delaware, 2014
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$3.2MraisedJan 2016 · 31 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Alexandra LatypovaExecutive Officer, Director, Promoter
  • Brian ModelDirector
  • J. Mikael TottermanExecutive Officer, Promoter
  • Arunas ChesonisDirector
  • Alex ZapesochnyExecutive Officer, Director, Promoter
  • David WilliamsDirector
Offering amount
$5M
Amount sold
$3.2M
Minimum investment
$5.6K
First sale
Dec 2015
Incorporated
Corporation, Delaware, 2014
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$2MraisedJan 2015 · 10 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • J. Mikael TottermanExecutive Officer, Promoter
  • David WilliamsDirector
  • Alex ZapesochnyExecutive Officer, Director, Promoter
  • Alexandra LatypovaExecutive Officer, Director, Promoter
  • Brian ModelDirector
  • Arunas ChesonisDirector
Offering amount
$3.7M
Amount sold
$2M
Proceeds to insiders
$425K
First sale
Dec 2014
Incorporated
Corporation, Delaware, 2014
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Company profile

researched Aug 2026

Clerio Vision is a development-stage medical device company built around LIRIC (Laser Induced Refractive Index Change), a femtosecond laser technique that alters the refractive index of materials such as hydrogels or corneal tissue without removing material or changing shape. Ultra-short laser pulses are used to write optical structures inside a lens or the eye by modifying material density at the molecular level, producing an optical rather than a structural change.

The company applies this single platform to four ophthalmic application areas: multifocal contact lenses for presbyopia, soft contact lenses designed to slow myopia progression in children, post-implant adjustment of intraocular lenses following cataract surgery, and incisionless corneal refractive correction as an alternative to conventional LASIK. Clerio states that first in-human LIRIC trials have been completed and that the platform is protected by more than 90 patents across more than 30 families, including more than 80 US patents.

Founding story

Clerio Vision originated from research at the University of Rochester, a center for optics research, conducted in collaboration with the Center for Visual Sciences. The company describes its origins in Nobel Prize-winning (2018) femtosecond laser physics research and says the underlying work began as a research collaboration in 2003 between femtosecond laser physicists and ophthalmology specialists.

Traction

Clerio reports completed first-in-human LIRIC trials, more than $80M of R&D investment, more than 90 patents across more than 30 families (including more than 80 US patents), and a financing round announced as successfully completed to accelerate development of the LIRIC contact lens platform.

Latest developments

In April 2026 Clerio announced a patent for an "Enhanced LIRIC" vision correction design covering trifocal and extended-range optics, and said it would present what it described as the world's first LCA-correcting soft contact lens at the ARVO 2026 Annual Meeting, with diffractive lenses fabricated using LIRIC shown to correct, neutralize or reverse longitudinal chromatic aberration, an optical cue implicated in myopia progression. The company also announced the successful completion of a financing round intended to accelerate development of the LIRIC contact lens platform.

Full profile — market position, technology, go-to-market, geography

Market position

Clerio positions LIRIC as one platform addressing four multi-billion-dollar ophthalmic segments, including a stated $2.5B global presbyopia market, and frames this cross-segment applicability as unusual among both startups and incumbents.

Differentiation is based on refractive index change without cutting, ablation or shape change, enabling diffractive and GRIN optical structures that the company says are impossible to produce by molding, post-surgical adjustability of implanted lenses, and repeatable corrections that can be updated as vision changes.

Technology

The core technology, LIRIC, uses ultra-short femtosecond laser pulses to change the refractive index of hydrogels or corneal tissue without cutting, ablation or removal of material. Computer-generated micro-patterns and proprietary diffractive structures that the company says cannot be molded are written inside lens material, enabling gradient-index (GRIN) optics, customizable optical zones, and corrections that can be updated or adjusted over time. In the intraocular application, corrective optics are written into an IOL after implantation, working with standard IOL materials and allowing a monofocal lens to be given multifocal optics. In the corneal application, the refractive index of the cornea is altered without a flap or tissue removal, which the company says preserves corneal structural integrity and reduces dry eye risk because nerves are not severed.

Go-to-market

The company presents itself as seeking partners and investors to commercialize the LIRIC platform across its four application areas, and lists partners and backing from investors on its website.

Patients with refractive error and age-related vision loss, including the presbyopic population (described as nearly everyone over 45, or roughly 1.8 billion people), children at risk of myopia progression, cataract patients with residual refractive error after IOL implantation (approximately 30% of cases), and prospective refractive surgery patients deterred by the cutting involved in conventional LASIK.

Geography

Rooted in research at the University of Rochester in the United States, with programs framed against global patient populations.

Compiled by commissioned research from 1 cited public sources — announcements, filings, and press listed under research sources below.

Key figures

latest reported
HeadcountAug 202639
R&D investmentJan 2026$80M
Targeted ophthalmic market segmentsJan 20264 segments

Company-reported or press-reported figures, each dated to when it was claimed — not independently audited.

Non-dilutive funding · 2 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
National Science FoundationPhase IISTTR2017$750K
National Science FoundationPhase ISTTR2016$225K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

Timeline · 3

launches, deals, and filings
Apr 2026
Presentation of LCA-correcting soft contact lens at ARVO 2026

Clerio Vision announced it would present diffractive soft contact lenses fabricated with LIRIC that correct, neutralize or reverse longitudinal chromatic aberration, an optical cue implicated in myopia progression.

source ↗

Apr 2026
Patent secured for "Enhanced LIRIC" vision correction design

Clerio Vision announced a new patent supporting trifocal and extended-range vision correction designs.

source ↗

Jan 2026
Clerio Vision announces successful completion of financing round

Company press release stating a financing round was completed, with proceeds to accelerate development of the LIRIC contact lens platform.

source ↗

Dated company events from announcements, filings, and press; legal rows summarize public dockets and regulator releases.

Research sources · 1

primary sources listed

1 public sources were cited for this profile; the first-party ones are listed here.

Frequently asked questions

What does Clerio Vision do?
Development-stage medical device company applying its LIRIC femtosecond laser platform across four ophthalmic markets.
Who are Clerio Vision's investors?
Clerio Vision's investors include Safar Partners, Armory Square Ventures, UpVentures Capital.
How much funding has Clerio Vision raised?
Clerio Vision has disclosed $28.9M raised across 5 rounds.
Where is Clerio Vision headquartered?
Clerio Vision is headquartered in Rochester, US.