Sharon Shacham
InvestorPhD, MBA | Managing Partner at E44 Ventures
Tel Aviv, Israel
Writes $1M – $5M checks · typically $2M
Find your path to Sharon
213 people in our graph share verified history with Sharon — schools, employers, funds. One of them is your warm intro.
Ittai HarelunlockedSharon: together at Protai (2022–2026)
Sharon: together at Sporos Bioventures
×5Sharon: together at E44 Ventures
×2Sharon: together at Gigablue
About
Drug inventor and entrepreneur who founded two NASDAQ companies (KPTI, EPIX) and raised over $750M. She serves as an active board member for multiple biotech ventures and holds a PhD in Computational Biophysics & Biochemistry and an MBA.
Experience
- E44 VenturesCo-Founder and Managing Directorcurrent2022 — presentTel Aviv, Israel
- phelasAdvisory Boardcurrent2023 — present
- GigablueBoard Observercurrent2023 — present
- CarbonadeBoard Observercurrent2023 — present
- AgriPassBoard Membercurrent2023 — present
- Karyopharm Therapeutics Inc.Foundercurrent2009 — present
- Karyopharm Therapeutics Inc.Scientific Advisory Board Membercurrent2009 — present
- Karyopharm Therapeutics Inc.Chief Scientific Officer2021 — 2022Newton, Massachusetts, United States
- Karyopharm Therapeutics Inc.President and CSO2011 — 2021Newton, Massachusetts, United States
- Karyopharm Therapeutics Inc.CEO and President2009 — 2011
- Sporos BioventuresScientific and Clinical Advisorcurrent2021 — present
- Acrivon Therapeutics, Inc.Board Membercurrent2021 — present
- Merlin HealthBoard Membercurrent2021 — present
- ProtaiScientific Advisorcurrent2022 — present
- Polaroid TherapeuticsCo-Founder2021 — 2022Zurich, Switzerland
- EPIX PharmaceuticalsSVP Drug Development2000 — 2009
- Predix PharmaceuticalsDirector, Algorithm and Software Development2000 — 2003
Investments
Investor
Per curated public sources.
What founders say
No founder feedback on Sharon Shacham yet.
Colleagues at E44 Ventures
Adi Vagman
Managing Partner at E44 Ventures
Anat Haas Mizrahi
Managing Partner at E44 Ventures
Dr. Udi Netzer
Scientific Partner at E44 Ventures
Ebony Archie
Manager | Digital Marketing & Communications at Camelback Ventures
Eli Waxman
Scientific Partner at E44 Ventures
Israel Bar Joseph
Scientific Partner at E44 Ventures
Prof. Eli Waxman
Scientific Partner at E44 Ventures
Prof. Israel Bar Joseph
Scientific Partner at E44 Ventures
Frequently asked questions
- Who is Sharon Shacham?
- Drug inventor and entrepreneur who founded two NASDAQ companies (KPTI, EPIX) and raised over $750M. She serves as an active board member for multiple biotech ventures and holds a PhD in Computational Biophysics & Biochemistry and an MBA.
- Where does Sharon Shacham work?
- Sharon Shacham is PhD, MBA | Managing Partner at E44 Ventures.
- What check size does Sharon Shacham write?
- Sharon Shacham typically writes checks of $1M – $5M.
- What companies has Sharon Shacham invested in?
- Investments tracked here include Phelas.
- Where did Sharon Shacham go to school?
- Sharon Shacham studied at Tel Aviv University (PhD, Biochemistry and Computational Biophysics); Tel Aviv University (MBA, Information Systems).
Same school
Also attended Tel Aviv University799
Arnon DinurPartner at 83NorthYoram SnirPartner at 83NorthRaz MaysharSenior Manager at Qualcomm VenturesDavid GoldschmidtManaging Director, Head of the Fund at Samsung Catalyst FundAmit ShofarSr. Investment Director at Samsung Catalyst FundRutie AdarInvestments & Innovation Sr. Director, Israel at Samsung Catalyst Fund
+ 793 more
Shared employers
Also worked at phelas2
Also worked at Karyopharm Therapeutics Inc.6
Ari ShamissCo-Founder, Managing General Partner at ALIVE Israel HealthTech FundDeepa PakianathanGeneral Partner at Delphi VenturesAnat Haas MizrahiManaging Partner at E44 VenturesStuart PoultonExecutive Officer at KaryopharmReshma RangwalaExecutive Officer at KaryopharmRichard PaulsonExecutive Officer, Director at Karyopharm
































