Jonathan Mandelbaum
InvestorPrincipal at OrbiMed
New York, New York
Writes $1M – $75M checks · typically $4M
About
Jonathan Mandelbaum is a Principal at OrbiMed, a healthcare venture capital firm. He previously worked as a drug discovery scientist and focuses on biotech company formation and medicine development.
Experience
- OrbiMedPrincipalcurrent2025 — presentNew York, New York, United States
- OrbiMedVice President2022 — 2025New York, New York, United States
- OrbiMedSenior Associate2020 — 2022Greater New York City Area
- Accelerator Life Science PartnersPrincipal2017 — 2020Greater New York City Area
- Accelerator Life Science PartnersAssociate2015 — 2017New York, New York
- Takeda OncologyScientist I2013 — 2015cambridge, massachusetts
- Takeda OncologyPostdoctoral Fellow2011 — 2013
- Columbia University Medical CenterPostdoctoral Fellow2010 — 2011
- Columbia University Medical CenterGraduate Research Assistant2005 — 2010
Education
- Columbia UniversityPh.D. (with Distinction), Cellular2005 — 2010
- McGill UniversityB.Sc. (with Great Distinction), Biology2001 — 2005
Skills & more
Molecular Biology15Cell CultureLifesciencesWestern BlottingDrug Discovery13Tissue CultureImmunohistochemistryMicroscopyImmunologyBiotechnology12Oncology12target validation
+12 more
Biomarker DiscoveryCellular AssaysFlow CytometryshRNAsiRNAMolecular GeneticsMechanism Of Action StudiesCancer Cell BiologyImmunofluorescenceMetabolismIn VivoMouse ModelsLanguages English · French · Hebrew
From Jonathan's professional profile.
Colleagues at OrbiMed
Frequently asked questions
- Where does Jonathan Mandelbaum work?
- Jonathan Mandelbaum is Principal at OrbiMed.
- What check size does Jonathan Mandelbaum write?
- Jonathan Mandelbaum typically writes checks of $1M – $75M.
Same school
Also attended Columbia University687
Ben HorowitzCo-founder & General Partner at Andreessen HorowitzDoug LeonePartner at Sequoia Capital; former Global Managing PartnerChris DixonFounder & Managing Partner of a16z crypto at Andreessen HorowitzGabriella GiglioHR & Executive Talent at General CatalystScott BillerInvestor at GV (Google Ventures)Erica VanInvestment Director at Intel Capital
+ 681 more
Also attended McGill University411
Harley FinkelsteinInvestor at Felicis VenturesMattias LjungmanInvestor at Moonfire VenturesNoubar AfeyanInvestor at Flagship PioneeringDavid NaultGeneral Partner at Luge CapitalLaviva MazharPrincipal at Luge CapitalLisa PurcellInvestor at Third Rock Ventures
+ 405 more
Shared employers
Also worked at OrbiMed48
Leon ChenPartner at The Column GroupTadd WesselManaging Partner at Scion Life SciencesAnna BittonInvestor at Dimension CapitalArvind ChariPrincipal at Eight Roads VenturesCarl GordonManaging Partner at OrbiMedW. Carter NeildManaging Partner at OrbiMed
+ 42 more
Also worked at Accelerator Life Science Partners4
Also worked at Takeda Oncology27
David SchenkeinInvestor at GV (Google Ventures)Kevin MunnellyInvestor at Third Rock VenturesJohn KeiltyVenture Partner at Third Rock VenturesKevin GillisPartner and Chief Operating Officer at Third Rock VenturesNeil ExterRetired Partner at Third Rock VenturesRobert TepperPartner and co-founder of Third Rock Ventures
+ 21 more
Also worked at Columbia University Medical Center19
Lisa PurcellInvestor at Third Rock VenturesIsaac ZikeManaging Director at RiverVest Venture PartnersHalle TeccoFounder, Rock Health & Natalist at Giant Ventures Global LlpAudreyInvestment Team Member at Acadian Ventures Management, LlcChris BostickPartner at OCV PartnersHJ HongAssociate at Romulus Capital
.png)
+ 13 more