Where does Jonathan Mandelbaum work?

Jonathan Mandelbaum is Principal at OrbiMed.

What check size does Jonathan Mandelbaum write?

Jonathan Mandelbaum typically writes checks of $1M – $75M.

Where did Jonathan Mandelbaum go to school?

Jonathan Mandelbaum studied at Columbia University (Ph.D. (with Distinction), Cellular, Molecular and Biophysical Studies); McGill University (B.Sc. (with Great Distinction), Biology).

Jonathan Mandelbaum

Investor

Principal at OrbiMed

New York, New York

Writes $1M – $75M checks · typically $4M

Find your path to Jonathan

531 people in our graph share verified history with Jonathan — schools, employers, funds. One of them is your warm intro.

Harley FinkelsteinunlockedJonathan: together at McGill University (2001–2003)

×2Jonathan: together at Columbia University Medical Center

×7Jonathan: together at Columbia University

Jonathan: together at McGill University

About

Jonathan Mandelbaum is a Principal at OrbiMed, a healthcare venture capital firm. He previously worked as a drug discovery scientist and focuses on biotech company formation and medicine development.

Experience

OrbiMedPrincipalcurrent2025 — presentNew York, New York, United States
OrbiMedVice President2022 — 2025New York, New York, United States
OrbiMedSenior Associate2020 — 2022New York City Metropolitan Area
Accelerator Life Science PartnersPrincipal2017 — 2020New York City Metropolitan Area
Accelerator Life Science PartnersAssociate2015 — 2017New York, New York
Takeda OncologyScientist I2013 — 2015cambridge, massachusetts
Takeda OncologyPostdoctoral Fellow2011 — 2013
Columbia University Medical CenterPostdoctoral Fellow2010 — 2011
Columbia University Medical CenterGraduate Research Assistant2005 — 2010

Skills & more

Molecular Biology15Cell CultureLifesciencesWestern BlottingDrug Discovery13Tissue CultureImmunohistochemistryMicroscopyImmunologyBiotechnology12Oncology12target validation

+8 more

Biomarker DiscoveryCellular AssaysFlow CytometryshRNAsiRNAMolecular GeneticsMechanism Of Action StudiesCancer Cell Biology

Languages English · French

From Jonathan's professional profile.

Colleagues at OrbiMed

Aldo Brambilla

Associate at Silver Lake Partners

Alexander M. Cooper

Investor at OrbiMed

Anat Naschitz

Executive Officer at OrbiMed

Anat Nursella

Venture Partner at OrbiMed

Andrew P. Kanarek, CFA, CIPM

Investor at Insight Partners

Frequently asked questions

Who is Jonathan Mandelbaum?: Jonathan Mandelbaum is a Principal at OrbiMed, a healthcare venture capital firm. He previously worked as a drug discovery scientist and focuses on biotech company formation and medicine development.
Where does Jonathan Mandelbaum work?: Jonathan Mandelbaum is Principal at OrbiMed.
What check size does Jonathan Mandelbaum write?: Jonathan Mandelbaum typically writes checks of $1M – $75M.
Where did Jonathan Mandelbaum go to school?: Jonathan Mandelbaum studied at Columbia University (Ph.D. (with Distinction), Cellular, Molecular and Biophysical Studies); McGill University (B.Sc. (with Great Distinction), Biology).

Same school

Also attended Columbia University1,302

Ben HorowitzCo-founder & General Partner at Andreessen Horowitz Doug LeonePartner at Sequoia Capital; former Global Managing Partner Chris DixonFounder & Managing Partner of a16z crypto at Andreessen Horowitz Kai-Fu LeeChairman of Sinovation Ventures and CEO of 01.AI Gabriella GiglioHR & Executive Talent at General Catalyst Scott BillerInvestor at GV (Google Ventures)

+ 1,296 more

Also attended McGill University768

Harley FinkelsteinInvestor at Felicis Ventures Mattias LjungmanInvestor at Moonfire Ventures Noubar AfeyanInvestor at Flagship Pioneering David NaultGeneral Partner at Luge Capital Laviva MazharPrincipal at Luge Capital Lisa PurcellInvestor at Third Rock Ventures

+ 762 more

Shared employers

Also worked at OrbiMed84

Ryan LoggieDirector of Finance and Tax at Casdin Capital Matthew R. PattersonVenture Partner - US Investments at SR One Capital Management Leon ChenPartner at The Column Group Anna BittonCFO at Torch Capital Ken TangPrincipal at K2 HealthVentures Tadd WesselManaging Partner at Scion Life Sciences

+ 78 more

Also worked at Accelerator Life Science Partners6

Marian NakadaVice President, Venture Investments at JJDC Asish K. XavierVice President, Venture Investments at JJDC Ross LeimbergFounder / EIR at 82VS Katie HewittInvestor at BlueYard Capital Thong Q. LeChief Executive Officer at Automera Imran AlibhaiChief Executive Officer at Tvardi Therapeutics

Also worked at Takeda Oncology52

David SchenkeinInvestor at GV (Google Ventures)Kevin MunnellyInvestor at Third Rock Ventures John KeiltyVenture Partner at Third Rock Ventures Kevin GillisPartner and Chief Operating Officer at Third Rock Ventures Neil ExterRetired Partner at Third Rock Ventures Robert TepperPartner and co-founder of Third Rock Ventures

+ 46 more

Also worked at Columbia University Medical Center42

Lisa PurcellInvestor at Third Rock Ventures Isaac ZikeManaging Director at RiverVest Venture Partners Coco DongDirector, Quantitative Applications at Deerfield Management Company Halle TeccoFounder, Rock Health & Natalist at Giant Ventures Global Llp AudreyInvestment Team Member at Acadian Ventures Management, Llc Tarek El-SawyVenture Partner at Raiven

+ 36 more