Brian Matthews
InvestorGeneral Partner at Cultivation Capital · Board director at SimpleRose · Manager at Tunespeak · Board director at Systematic Revenue
St. Louis, Missouri
Writes $100K – $3.5M checks · typically $1.8M
About
Brian Matthews is an operator-turned-investor who built and exited multiple internet companies, a Seed 100–recognized mentor central to St. Louis startups who teaches founders investment-readiness with a mechanical engineering lens.
Contact· self-published, not guessed
Invests in
AgTechBiotechFintechFoodTechHealthtechSaaS
Board director at SimpleRose
Intro paths
In turn, Brian can intro founders to SimpleRose's investors below.
Manager at Tunespeak
Intro paths
In turn, Brian can intro founders to Tunespeak's investors below.
Tunespeak's investors · 3
Co-founders at Tunespeak
Board director at Systematic Revenue
Intro paths
In turn, Brian can intro founders to Systematic Revenue's investors below.
Systematic Revenue's investors · 1
Co-founders at Systematic Revenue
Experience
- Cultivation CapitalGeneral Partnercurrent2012 — presentGreater St. Louis
- SimpleRoseBoard Membercurrent2018 — presentGreater St. Louis
- OpsLabMember Board of Directorscurrent2024 — present
- FinOpslyMember Board of Directorscurrent2026 — present
- DecideBoard of Directorscurrent2010 — presentGreater St. Louis
- HatchbuckBoard of Directorcurrent2012 — presentGreater St. Louis
- TunespeakBoard of Directorscurrent2013 — presentGreater St. Louis
- TechSTLBoard Presidentcurrent2022 — presentSt. Louis, MO
- S4Member Board of Directorscurrent2016 — presentBuenos Aires, Buenos Aires Province, Argentina
- aisle411 Inc.Chairman of the Boardcurrent2014 — presentGreater St. Louis
- River City Internet GroupOwnercurrent2001 — present
- Friends of T-REXMember Board of Directorscurrent2013 — presentSt. Louis, MO
- Capital InnovatorsInvestor/Mentorcurrent2011 — presentSt. Louis, MO
- Regional Business CouncilMember2017 — 2024Greater St. Louis
- PerficientMember Board Of Directors2017 — 2024St. Louis, MO
- University of MO - St. LouisMember of Chancellor's Council2017 — 2023Greater St. Louis
- NoonLight, Inc.Member of Board of Directors2016 — 2022Greater St. Louis
- TopOPPSMember Board of Directors2014 — 2021Greater St. Louis
- SixThirty Financial Technology AcceleratorDirector2013 — 2019Greater St. Louis Area
- GlobalHackBoard Member2014 — 2019Greater St. Louis
- Liberty Sports InteractiveExecutive Vice President2008 — 2010
- CDM Fantasy SportsCEO1991 — 2006
- Primary NetworkCEO1995 — 2000
- McDonnell DouglasLead Engineer1981 — 1992St. Louis
Skills & more
+12 more
SalesStart-upsBusiness DevelopmentFundraisingAngel InvestingMarketing StrategyInvestmentsMergers & AcquisitionsBusiness PlanningCorporate DevelopmentBusiness StrategyNew Business DevelopmentFrom Brian's professional profile.
Investments
Board seats
Aisle411BenchmarkONE (Hatchbuck)LockerDomeNoonlightPerficientS4SimpleRoseTunespeak
Per the firm's website.
Colleagues at Cultivation Capital
Network11
Investors connected to Brian in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Brian Matthews?
- Brian Matthews is an operator-turned-investor who built and exited multiple internet companies, a Seed 100–recognized mentor central to St. Louis startups who teaches founders investment-readiness with a mechanical engineering lens.
- Where does Brian Matthews work?
- Brian Matthews is General Partner at Cultivation Capital and Board director at SimpleRose and Manager at Tunespeak and Board director at Systematic Revenue.
- What does Brian Matthews invest in?
- Brian Matthews invests in AgTech, Biotech, Fintech, FoodTech, Healthtech, SaaS.
- What check size does Brian Matthews write?
- Brian Matthews typically writes checks of $100K – $3.5M.
- What boards does Brian Matthews sit on?
- Brian Matthews holds tracked board seats at Aisle411, BenchmarkONE (Hatchbuck), LockerDome, Noonlight, Perficient, S4, SimpleRose, Tunespeak.
- Where did Brian Matthews go to school?
- Brian Matthews studied at Missouri University of Science and Technology (BS, Mechanical Engineering).
Same school
Also attended Missouri University of Science and Technology13
+ 7 more
Shared employers
Also worked at Decide1
Also worked at Perficient2
Also worked at McDonnell Douglas96
+ 90 more


























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