Misgav · Pre-Seed–Late Stage · 18 people tracked
Investment thesis
Trendlines invests in and builds innovation-based companies across agrifood technologies and medtech/healthcare. The firm engages early, backing companies from seed through to market and providing hands-on support drawing on its experience, network, and resources. Its focus areas span food technology (including novel food ingredients and colorings), agricultural technology (crop and field monitoring, sustainability), and a range of medical devices addressing conditions such as pelvic organ prolapse, bladder cancer, and orthopedic needs. The firm emphasizes taking companies through development toward commercialization and exits, as evidenced by acquisitions of portfolio companies by larger strategic players.
Source: firm website, verified Aug 3, 2026.
Team · 18 people
from the firm's website & public directories
Founder mafia
2 people who came through Trendlines Group went on to found or lead other companies.
What they invest in
from 21 of 52 portfolio companiesMedical Devices ×14Biotech ×10Healthtech ×10FoodTech ×5AgTech ×4Hardware ×3Climate Tech ×2Digital Health ×2
HQs:Israel×6United States×1
Investments · 52 tracked
founders shown can be your intro pathSingapore agri-fintech turning rice farmers' agronomic data into credit signals to unlock lending and cut methane emissions.
Integrates field, air, and space data to detect agribio risks and provide sustainability monitoring insights.
Co-investorsPrelude Ventures
Arcuro Medical develops the SuperBall all-suture soft-tissue repair system for orthopedic surgeons performing meniscal and rotator cuff procedures.
HealthtechMedical Devices
Co-investorsVaranaConsensus Business Group
Singapore-based medical device company developing an automated body pressure redistribution system to help prevent pressure ulcers.
BeCapio develops a non-invasive medical device system to treat fecal incontinence (accidental bowel leakage), combining electrical stimulation of the anal sphincters and pelvic muscles with a sealing plug for immediate leak prevention.
HardwareHealthtechMedical Devices
Dan Livovsky(Co-Founder | Medical Director)inJoseph Lysy(Co-Founder | Medical Director)Gil Senesh(CEO)in
BoardAndy Weymann(Chairman of Board)in
Biosight was a pharmaceutical company that merged with Ayala Pharmaceuticals on October 19, 2023.
Biotech
Celleste Bio develops a cell-based "cocoa technology" combining biotech, agtech, and AI to produce real cocoa ingredients—including cocoa butter and powder—at scale independent of geography and climate.
AgTechBiotechFoodTech
Hanne Volpin(Founder)in
Co-investorsBarrel VenturesFLORA VenturesConsensus Business GroupSUPPLY CHANGE CAPITAL
Ceretrieve Ltd. develops neurointerventional medical devices, including distal access catheters, thrombectomy devices, and related accessories, working with physicians to improve device performance and patient outcomes.
HealthtechMedical Devices
Medical device company developing a minimally invasive handheld device to reduce urine leakage from stress urinary incontinence.
Israeli med-tech company developing noninvasive directional skin tightening technology for non-surgical breast lifting.
Singapore medical device startup developing devices and blades for faster scar revision and skin biopsy procedures.
Develops a compression device for the treatment of venous conditions.
Co-investorsPix Vine Capital
Singapore medical technology company developing an app that analyzes real-time images of the bladder.
Escala Medical develops an incision-free, FDA-cleared outpatient procedure for repairing pelvic organ prolapse, aimed at restoring pelvic floor function in women.
FemTechHealthtechMedical Devices
Israeli maker of airway tubes with built-in cameras for lung isolation and difficult intubations, acquired by Ambu A/S in 2016.
Gordian Surgical develops the TroClose, an FDA-cleared integrated trocar and wound closure device that combines laparoscopic port access with automated port-site closure.
HardwareMedical Devices
Co-investorsMing capital
Harp Diagnostics is developing Harp 360, a remote patient monitoring platform for inflammatory bowel disease (Crohn's disease and ulcerative colitis) and other GI conditions, combining a home sample collector with an automated cloud-connected testing system.
Digital HealthHealthtechMedical DevicesMisgav, IL
IBI-Ag develops selective bio-insecticides based on single domain antibody technology that target specific proteins in insect pests, aimed at helping farmers protect crops with minimal harm to workers, consumers, and the environment.
AgTechBiotechFoodTech
Rony Oren Benaroya(Founder & Chief Technology Officer)Amir Ayali(Founder & Scientific Advisor)Arnon Heyman(Chief Executive Officer)
Co-investorsFirst Imagine!
Israeli medical device company that developed a microlaparoscopy platform for scar-free laparoscopic surgery; acquired by Teleflex in 2013.
Israeli medical device company behind Inspiromatic, a smart dry powder inhaler for respiratory disease, acquired by OPKO Health in 2014.
Singapore medical device company developing urological catheters aimed at urinary tract infection.
iRen Medical (formerly liberDi) develops an FDA-cleared home dialysis platform for peritoneal dialysis patients, including an automated ambulatory PD exchange device, letting patients perform dialysis at home or work while providers monitor outcomes remotely.
Digital HealthHealthtechMedical DevicesMisgav, IL
Israeli medical device company developing PRECISION-GI, a motorized endoscopic ultrasound-guided core biopsy device.
Singapore medical device company developing a real-time ultrasound-guided needle insertion system for lumbar punctures.
Israeli medical device company developing a transcatheter mitral valve implant for patients at high surgical risk.
Singapore medtech developing an ultrasound-based nasogastric tube system that verifies tube tip placement in real time.
NeuroQuest is developing NeuroScreen®, a blood-based biomarker screening test for early detection of Alzheimer's disease.
Singapore medtech developing an AI eye-tracking system for home monitoring of central vision loss in AMD patients.
Acquired by Synthes GMBH (DePuy Synthes, Johnson & Johnson) in November 2021.
Israeli developer of laparoscopic hernia mesh placement devices, acquired by Covidien in April 2012.
PregnanTech develops a silicone medical device placed around the uterine cervix to help keep the cervix elongated, addressing preterm birth.
FemTechHealthtechMedical DevicesMisgav, IL
Co-investorsSteelSky VenturesLauder Partners
Israeli medical device company developing ClearRing, a minimally invasive implant-based treatment for benign prostatic hyperplasia.
Israeli medical device company developing SEGER IDEA, a laparoscopic stapler for fully intracorporeal bowel anastomosis.
SetBone Medical is developing a new type of bone cement for treating vertebral compression fractures, which are primarily caused by osteoporosis.
BiotechMedical DevicesNew Materials
Israeli developer of a solar-panel-on-a-chip that powers maintenance-free IoT sensing and control systems.
Israeli developer of low-profile colostomy management devices based on Artificial Ostomy Sphincter technology.
Singapore medtech developing Tenogarde, an implant that reinforces the suture-tendon interface in rotator cuff repair.
Vensica is a clinical-stage medical company developing ViXe, a needle-free treatment for overactive bladder that combines the neurotoxin Xeomin with Vibe, an ultrasound-based drug delivery device that microinjects medication into the bladder wall.
BiotechHealthtechMedical Devices
Avner Geva(CEO, Co-founder)Avi Eftel(CTO, Co-founder)Roger R. Dmochowski(CMO)Ken Berlin(Executive Chairman)
Co-investorsIsrael Biotech Fund
Vessi Medical develops a minimally invasive cryo spray system for treating urological conditions in the bladder, offering a non-surgical alternative to traditional procedures performed in hospital settings.
HealthtechMedical DevicesNesher, IL
Eyal Kochavi(CEO & Founder)
Co-investorsALIVE Israel HealthTech Fund
ViAqua develops an orally administered, particle-based platform that encapsulates RNA in feed to prevent viral diseases in shrimp and other aquaculture species.
AgTechBiotechFoodTech
Co-investorsS2G InvestmentsRabo Ventures
Israeli medical device company developing adjustable facial implants that can be modified after surgery without further operations.
Zygofix develops spinal fixation implants for lumbar spinal fusion, aimed at surgeons and patients in the Ambulatory Surgery Center (ASC) market.
HardwareMedical Devices
Exits · 1
IPOs and acquisitions across the tracked portfolioOrthoSpinacq. by Synthes
Portfolio news
latest coverage across their companiesCelleste Bio · foodnavigator.com · Oct 15, 2025
Frequently asked questions
- How many investments has Trendlines Group made?
- Trendlines Group has 53 tracked investments, 1 of which have exited via acquisition or IPO.
- What stage does Trendlines Group invest at?
- Trendlines Group invests at the Pre-Seed, Seed, Series A, Late Stage stages.
- What is Trendlines Group's typical check size?
- Trendlines Group typically writes checks of $650K – $15M.
- What sectors does Trendlines Group focus on?
- Trendlines Group focuses on AgTech, Biotech, Cleantech, Digital Health, Energy, Enterprise Software, FoodTech, Healthtech, Medical Devices, New Materials, SaaS.
- Where is Trendlines Group located?
- Trendlines Group is headquartered in Misgav, IL.
- Who does Trendlines Group co-invest with?
- Trendlines Group most often shares deals with Prelude Ventures, Brighteye Ventures, Eight Roads Ventures, among 37 tracked co-investors.
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