Fundraising Fox
Misgav · Pre-Seed–Seed · 20 people tracked
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Investment thesis
Trendlines invests in and builds innovation-based companies across agrifood technologies and medtech/healthcare. The firm engages early, backing companies from seed through to market and providing hands-on support drawing on its experience, network, and resources. Its focus areas span food technology (including novel food ingredients and colorings), agricultural technology (crop and field monitoring, sustainability), and a range of medical devices addressing conditions such as pelvic organ prolapse, bladder cancer, and orthopedic needs. The firm emphasizes taking companies through development toward commercialization and exits, as evidenced by acquisitions of portfolio companies by larger strategic players.
Source: firm website, verified Sep 27, 2026.
Team · 20 people
from the firm's website & public directories
Founder mafia
5 people who came through Trendlines Group went on to found or lead other companies.
What they invest in
from 21 of 52 portfolio companiesMedical Devices ×14Biotech ×11Healthtech ×11FoodTech ×5AgTech ×4Hardware ×3New Materials ×3Climate Tech ×2
HQs:Israel×10United States×2
Who they back
founder profiles across 10 portfolio companiesFounding team size:solo founder×52 founders×5
Where their founders studiedfrom 12 founders with education data
Technion ×4The Hebrew University of Jerusalem ×4Weizmann Institute of Science ×4Tel Aviv University ×3University of Haifa ×2
What their founders studiedfrom 11 founders with field-of-study data
Life Sciences ×7Engineering ×4
Investments · 52 tracked
founders shown can be your intro pathSingapore agri-fintech turning rice farmers' agronomic data into credit signals to unlock lending and cut methane emissions.
Co-investorsBetter Bite Ventures
ApiFix develops treatment solutions for pediatric scoliosis, operating as a subsidiary of OrthoPediatrics Corp.
HealthtechMedical DevicesWarsaw, US
Adi Toisterin
Co-investorsIsrael Innovation Authority
Arcuro Medical develops all-suture soft-tissue repair technologies for orthopedic surgeons, with its flagship SuperBall® System providing knotless fixation for meniscal and rotator cuff procedures.
HealthtechMedical Devices
Co-investorsVaranaConsensus Business Group
BeCapio develops a non-invasive medical device system to treat fecal incontinence (accidental bowel leakage), combining electrical stimulation of the anal sphincters and pelvic muscles with a sealing plug for immediate leak prevention.
HardwareHealthtechMedical Devices
Dan Livovsky(Co-Founder | Medical Director)inJoseph Lysy(Co-Founder | Medical Director)Gil Senesh(CEO)in
BoardAndy Weymann(Chairman of Board)in
Biosight was a pharmaceutical company that merged with Ayala Pharmaceuticals on October 19, 2023.
Biotech
Co-investorsSBI JI Innovation Advisory Ltd.Israel Biotech Fund
Celleste Bio develops a cell-based "cocoa technology" combining biotech, agtech, and AI to produce real cocoa ingredients—including cocoa butter and powder—at scale independent of geography and climate.
AgTechBiotechFoodTech
Hanne Volpin(Founder)in
Co-investorsBarrel VenturesFLORA VenturesConsensus Business GroupSUPPLY CHANGE CAPITAL
Ceretrieve Ltd. develops neurointerventional medical devices, including distal access catheters, thrombectomy devices, and related accessories, working with physicians to improve device performance and patient outcomes.
HealthtechMedical Devices
Co-investorsIsrael Innovation Authority
CoreBone cultivates corals in a closed lab-based aquarium system to produce natural scaffolds for bone and cartilage tissue engineering, offering dental bone grafts as an alternative to bovine and human grafts.
BiotechMedical DevicesNew Materials
Ohad Schwartz(CEO & Co-founder)in
Ecophage develops environmental solutions branded as proprietary products addressing sustainability challenges.
AgTechBiotechCircular EconomyCleantechClimate Tech
Co-investorsIsrael Innovation Authority
Develops a compression device for the treatment of venous conditions.
Co-investorsPix Vine Capital
Escala Medical develops advanced medical devices for pelvic organ prolapse repair, targeting women seeking to restore quality of life.
FemTechHealthtechMedical Devices
Edit Goldberg(CEO)in
Co-investorsConsensus Business Group
Gordian Surgical develops innovative wound closure solutions for laparoscopic and robotic surgeries, designed to enhance surgical efficiency and patient outcomes.
HardwareMedical Devices
Co-investorsMing capitalVirtus Inspire Ventures
Harp Diagnostics is developing Harp 360, a remote patient monitoring platform for inflammatory bowel disease (Crohn's disease and ulcerative colitis) and other GI conditions, combining a home sample collector with an automated cloud-connected testing system.
Digital HealthHealthtechMedical DevicesMisgav, IL
IBI-Ag develops selective bio-insecticides based on single domain antibody technology that target specific proteins in insect pests, aimed at helping farmers protect crops with minimal harm to workers, consumers, and the environment.
AgTechBiotechFoodTech
Rony Oren Benaroya(Founder & Chief Technology Officer)inAmir Ayali(Founder & Scientific Advisor)inArnon Heyman(Chief Executive Officer)in
Co-investorsFirst Imagine!Bandera CapitalConsensus Business GroupIsrael Innovation Authority
iRen develops medical technology for dialysis patients, enabling them to continue daily activities while undergoing treatment.
BiotechDigital HealthHealthtechMedical DevicesMisgav, IL
Phytolon produces natural food colors derived from baker's yeast fermentation technology, offering vivid hues with heat stability and clean label credentials for food manufacturers.
BiotechClimate TechFoodTechNew Materials
Halim Jubran(Co-founder & CEO)inTal Zeltzer(Co-founder & CTO)in
Co-investorsCIBUS ENTERPRISE FUND II LPColorcon Ventures
PregnanTech develops a silicone medical device placed around the uterine cervix to help keep the cervix elongated, addressing preterm birth.
FemTechHealthtechMedical DevicesMisgav, IL
Co-investorsSteelSky VenturesLauder Partners
SetBone Medical develops solutions for spinal care and orthopedic applications.
BiotechHealthtechMedical DevicesNew Materials
Royi Kaufmann(CTO & Co-Founder)in
Vensica is a clinical-stage medical company developing ViXe, a needle-free treatment for overactive bladder that combines the neurotoxin Xeomin with Vibe, an ultrasound-based drug delivery device that microinjects medication into the bladder wall.
BiotechHealthtechMedical Devices
Avner Geva(CEO, Co-founder)inAvi Eftel(CTO, Co-founder)inRoger R. Dmochowski(CMO)Ken Berlin(Executive Chairman)in
Co-investorsIsrael Biotech Fund
Vessi Medical develops a minimally invasive cryo spray system for treating urological conditions in the bladder, offering a non-surgical alternative to traditional procedures performed in hospital settings.
HealthtechMedical DevicesNesher, IL
Eyal Kochavi(CEO & Founder)in
Co-investorsALIVE Israel HealthTech Fund
ViAqua Therapeutics develops RNA-based solutions to treat diseases in aquaculture, specifically targeting viral pathogens like White Spot Shrimp Virus in shrimp through oral feed application.
AgTechAI & Machine LearningBiotechFoodTech
Shai Ufaz(CEO & Co-Founder)inShai Einbinder(Co-Founder)in
Co-investorsS2G InvestmentsIsrael Innovation AuthorityRabo VenturesRabo Corporate Venturing
ZygoFix develops minimally invasive fixation solutions for joint stabilization and fusion procedures, targeting the ambulatory surgery center market.
HardwareMedical Devices
Uri Arnin(Co-Founder, CTO)Ofer Levy(CEO)in
Co-investorsIsrael Innovation Authority
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AgroScoutAlgahealthAyzer SenseContinale MedicalDasyoDermcut MedicalEndosiqEtviewFlowsenseInnolap SurgicalInspiro MedicalIntervaalLimaca MedicalMedulla ProMitrassistNasotrak MedicalNeuroquestNice SurgicalOccutrackOrthoSpinPolytouch MedicalProarc MedicalSeger Surgical SolutionsSol ChipSt StentStimatix GiTendonplus MedicalTierraspecVisagex
Exits · 8
8 acquisitions · showing 1OrthoSpinacq. by Synthes
Portfolio news
latest coverage across their companiesPhytolon · finsmes.com · May 26, 2026
Escala Medical · prnewswire.com · Jun 30, 2025
Frequently asked questions
- How many investments has Trendlines Group made?
- Trendlines Group has 52 tracked investments, 8 of which have exited.
- What stage does Trendlines Group invest at?
- Trendlines Group invests at the Pre-Seed, Seed stages.
- What sectors does Trendlines Group focus on?
- Trendlines Group focuses on AgTech, Biotech, Cleantech, Digital Health, Energy, Enterprise Software, FoodTech, Healthtech, Medical Devices, New Materials, SaaS.
- Where is Trendlines Group located?
- Trendlines Group is headquartered in Misgav, IL.
- Who does Trendlines Group co-invest with?
- Trendlines Group most often shares deals with Barrel Ventures, Better Bite Ventures, Lauder Partners, among 16 tracked co-investors.
Images
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