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Third Security, LLC

Family office

Radford · Growth · 9 people tracked

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Investment thesis

Third Security manages a portfolio of operating biotechnology companies while also functioning as a family office. The firm collaborates closely with its portfolio companies to accelerate innovation and growth, with a focus on applying biology to solve problems around the world.

Source: firm website, verified Aug 3, 2026.

Stage
Growth
HQ
Radford, Virginia, US
Instruments
Equity
Founded
1999
Tracked investments
4

Team · 9 people

from the firm's website & public directories
Clifton R. Herndon· II, Managing Director and Controller
Doit L. Koppler· II, Managing Director and Treasurer

What they invest in

from 4 of 4 portfolio companies

Biotech ×4AgTech ×3FoodTech ×2AI & Machine Learning ×1Healthtech ×1Medical Devices ×1

HQs:United States×1

Investments · 4 tracked

founders shown can be your intro path
Precigenprecigen.comin𝕏NASDAQ: PGEN

Precigen is a biopharmaceutical company developing gene and cell therapies, including PAPZIMEOS (zopapogene imadenovec-drba), an FDA-approved immunotherapy for adults with recurrent respiratory papillomatosis.

BiotechHealthtechMedical DevicesGermantown, US

Thomas D. Reed(Executive Officer)Thomas R. Kasser(Executive Officer)Suma M. Krishnan(Executive Officer)Donald P. Lehr(Executive Officer)Robert F. Walsh, III(Executive Officer)Helen Sabzevari, PhD(President and CEO)

Co-investorsThird Point Ventures

GreenVenusgreenvenus.com

GreenVenus uses gene editing and advanced breeding technologies to improve crop resilience and productivity across the food value chain, serving agricultural producers and consumers.

AgTechBiotechFoodTech

Okanagan Specialty Fruitsosfruits.comin𝕏

Okanagan Specialty Fruits uses biotechnology to develop fruit varieties aimed at more efficient and sustainable food production.

AgTechBiotechFoodTech

Neal Carter(Founder and CEO)

Oxitecoxitec.comacquired by Precigen

Flyttr operates a biosecurity platform that develops and deploys countermeasures against pest threats, combining autonomous pest monitoring systems, AI-powered decision-support, and biological interventions such as engineered Aedes aegypti and Wolbachia.

AgTechAI & Machine LearningBiotech

Co-investorsH20 Venture PartnersRockley Group

Exits · 2

IPOs and acquisitions across the tracked portfolio

PrecigenNASDAQ: PGENOxitecacq. by Precigen

Portfolio news

latest coverage across their companies

Frequently asked questions

What stage does Third Security, LLC invest at?
Third Security, LLC invests at the Growth stage.
What sectors does Third Security, LLC focus on?
Third Security, LLC focuses on Biotech.
Where is Third Security, LLC located?
Third Security, LLC is headquartered in Radford, US.
Who does Third Security, LLC co-invest with?
Third Security, LLC most often shares deals with H20 Venture Partners, Rockley Group, Third Point Ventures, among 3 tracked co-investors.

Images

Third Security, LLC photoThird Security, LLC photoThird Security, LLC photoThird Security, LLC photo

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