NLC

Aerion Bioscience develops a non-invasive blood test that uses a 6-protein biomarker panel and an algorithm to detect early-stage lung cancer in high-risk individuals.

BiotechDigital HealthMedical Devices

Aetherus is developing a pocket-sized, non-pharmaceutical handheld device that provides positive-pressure breathing support to give rapid relief from acute breathlessness in about 2-3 minutes for patients with moderate to very severe COPD.

Digital HealthHardwareMedical Devices

AIDO develops a robotic add-on system, combining hardware and software, that attaches to existing endoscopes to assist endoscopists with complex, non-invasive procedures such as treating colorectal cancer and performing pancreatic biopsies.

HealthtechMedical DevicesRobotics

Allergios develops an in-vitro allergy diagnostic that visualizes allergic responses by analyzing how a patient's blood serum induces basophil degranulation, using a disposable microfluidic chip, an optical reader (GranulEye), and AI-based analysis software.

AI & Machine LearningDigital HealthMedical Devices

Altach Biomedical develops biomimetic cartilage scaffolds made from Type II collagen that surgeons use to repair cartilage defects and promote tissue regeneration, aiming to prevent progression to osteoarthritis.

BiotechHealthtechMedical DevicesDublin, IE

Amotio develops a guided bone cement removal system with patient-specific surgical planning and precision instrumentation for orthopaedic revision surgery, targeting arthroplasty and revision surgeons who work with cemented joint implants.

HardwareHealthtechMedical Devices

Iestyn Foster(Founder & CEO)

PCaVision is a diagnostic tool that combines multiparametric ultrasound imaging with AI algorithms to detect suspicious areas for prostate cancer, offering urologists a diagnostic pathway that does not require MRI.

AI & Machine LearningDigital HealthMedical Devices

Ansana develops a smart medical device with integrated sensors and real-time track-and-trace technology, plus data modules for quality release, scheduling, inventory optimization, and operating room service management, to manage surgical instrument reprocessing.

HealthtechIoTMedical Devices

Artifex Health develops small-diameter vascular grafts made from bacterial cellulose, aiming to combine natural biocompatibility with reproducible manufacturing.

BiotechHealthtechMedical Devices

Asclepius MedTech develops Surgfit, a remote patient monitoring platform that combines a Class IIa wearable biosensor patch with health questionnaire data to give hospital pre-operative and surgical teams continuous physiological data for preoperative surgical assessment and post-operative planning.

Digital HealthHealthtechMedical DevicesLeeds, GB

Next-generation polyurethane support system (Plielle) for treating stress urinary incontinence.

Audaxis Medical develops a next-generation implantable device for stress urinary incontinence (SUI), using a fascia-inspired polyurethane implant intended to improve safety and efficacy over existing pelvic health treatments.

FemTechHealthtechMedical Devices

Modular intramedullary nailing system for trauma treatment offering flexible bone alignment.

Axial Orthopaedics is developing a multicomponent intramedullary nail system for fixation of complex long bone fractures, designed to allow intraoperative component selection to reduce complications such as limb malalignment and compartment syndrome.

HealthtechMedical Devices

Bilihome develops a wearable phototherapy device that integrates hospital-grade blue light jaundice treatment into a soft cotton romper, allowing newborns to be treated without incubators, eye masks, or separation from parents.

Digital HealthHardwareMedical DevicesArnhem, NL

System allowing newborns to receive care with the umbilical cord intact until they breathe independently.

Concord Neonatal develops the Concord Birth Flow and Concord Birth Trolley, medical devices that enable Physiological-Based Cord Clamping so newborns—especially premature babies needing breathing support—can stay connected to the placenta and mother during resuscitation.

HardwareHealthtechMedical Devices

Developing small molecule antagonists.

Orally available small-molecule therapy targeting the RAGE/DIAPH1 pathway for metabolic and inflammatory conditions.

Early-stage drug delivery company.

Smart capsule technology for oral drug delivery of large molecules like biologics; a collaboration between NLC and Verily (Google) Life Sciences.

Exolvo Biosciences develops an oral drug delivery technology using "smart capsules" with dissolvable microneedles for large, complex molecules such as biologics, aiming to replace injections.

BiotechDeep TechMedical Devices

Scanner providing immediate imaging of biopsy and surgical specimens to distinguish healthy tissue from tumors in real time.

Foveo Fertility develops a medical device to improve egg cell quality and IVF laboratory workflow, aimed at fertility clinics and IVF lab professionals.

FemTechHealthtechMedical Devices

MaltaHip hip replacement implant with four independent parts for enhanced mobility and reduced dislocation risk.

Garland Surgical develops the TriActiv Hip (formerly MaltaHip), a total hip replacement implant using a patented tri-axial design intended to improve mobility, stability, and durability while reducing revision surgeries.

HardwareHealthtechMedical DevicesWorcester, GB

Simon Mifsud(Founder & Group Chief Executive Officer)John Shapland(Chief Technology Officer)

Haermonics is a clinical-stage medtech company that developed the Haermonics Pure System, a continuous postoperative pericardial flush therapy designed to keep chest tubes clear and prevent bleeding-related complications after open-heart cardiac surgery.

HardwareHealthtechMedical DevicesEindhoven, NL

David R. Koolbergen(Inventor of the therapy; Congenital Cardiothoracic Surgeon)

HapticHeart Solutions builds a device-agnostic system that converts biophysical and physiological signals from cardiac catheterization, electrophysiology, and robotic interventions into haptic feedback delivered to operators through a wearable interface and handle.

HardwareHealthtechMedical Devices

Wearable device giving cardiologists tactile feedback during catheter-based cardiac procedures.

Hemeo develops AI-based clinical decision support software that consolidates data from multiple sources to predict coagulation risks and personalize the prevention and treatment of bleeding and thrombosis.

AI & Machine LearningDigital HealthHealthtech

Handheld induction device that heats implants to eliminate bacteria causing prosthetic joint infections.

Implant Preservation Devices (IPD) develops a non-contact induction implant heating technology to treat prosthetic joint and fracture-related infections by eradicating bacterial biofilms on orthopaedic implants.

BiotechHealthtechMedical Devices

Catheter combining intravascular ultrasound and photoacoustic imaging (IVPA) for coronary artery disease treatment.

Kaminari Medical develops intracoronary imaging technology to visualize plaque within arteries for the assessment of coronary artery disease and to support clinical decision-making.

HealthtechMedical Devices

Lamina Therapeutics develops Lamina.One, a combined advanced therapy medicinal product for bone and cartilage regeneration that pairs a biodegradable polymeric membrane with hydroxyapatite and an autologous mesenchymal stem cell hydrogel to treat knee osteoarthritis and orthopaedic, maxillofacial, and periodontal conditions.

BiotechHealthtechMedical DevicesStrasbourg, FR

Nadia Benkirane-Jessel(Founder)Stephan Lemmens(CEO)

LarynxLock is a medical device that reduces air leakage from supraglottal airway devices by applying external upward pressure to the soft tissue at the base of the mouth to restore internal anatomy.

HardwareHealthtechMedical DevicesMaastricht, NL

Ledgy is a platform for managing non-cash compensation, including equity, deferred compensation, carried interest, pensions, and savings, with features for share plan administration, vesting schedules, cross-jurisdiction compliance reporting, and employee-facing dashboards.

FintechHR TechSaaS

Armon Bättig(Founder)inYoko Spirig(Founder)in

Loresa Health develops low-cost surgical aids for emerging markets, including RAIS, a retractor that enables gasless laparoscopy without CO2 insufflation or general anesthesia.

HardwareImpact & Social GoodMedical Devices

LUMABS BV develops RAPPID, a one-step mix-and-measure antibody detection technology for rapid, sensitive quantification of antibodies or antigens such as therapeutic drugs directly in biological samples including blood.

BiotechMedical Devices

MindAffect develops objective sensory assessment tools that use EEG-based brain-computer interface technology to measure neurological responses to sound and visual stimuli, enabling hearing and vision testing without requiring verbal or physical patient responses.

AI & Machine LearningHealthtechMedical Devices

Gene therapy delivering microRNA-335 via AAV9 viral vector for drug-resistant epilepsy.

Methylation-based test for personalized melanoma malignancy measurement and prognosis.

MLA Diagnostics develops prognostic tests for early-stage melanoma, using clinically relevant methylation markers to support treatment decisions.

BiotechDigital HealthMedical DevicesMaastricht, NL

Injectable bio-inductive protein extract from porcine notochordal biomatrix to treat degenerated intervertebral discs.

NC Biomatrix develops a non-cellular, non-opioid biologic therapy designed to trigger the body's natural regenerative mechanisms in cartilage tissue.

BiotechHealthtechMedical Devices

Developing small molecule therapies for neurodegenerative diseases.

NLV-01, a first-in-class non-opioid GalR2 agonist for peripheral neuropathy offering pain relief and nerve regeneration.

Nicolab builds StrokeViewer, an AI-powered, cloud-based platform for acute care teams that speeds up stroke triage by giving physicians fast access to DICOM imaging, patient timelines, and secure messaging across hospitals.

AI & Machine LearningDigital HealthMedical Devices

Merel Boers(Co-Founder)

Nilocas is developing a non-invasive medical device—a chest patch using microphones and accelerometers—that detects Coronary Heart Disease by capturing the sound of turbulent blood flow through narrowed arteries.

Digital HealthHardwareMedical Devices