Y Combinator Winter 2026 (W26) Companies

Synthetic Sciences develops foundation models trained on research process data to enable autonomous scientific work, combining data capture infrastructure with model training to create AI systems with scientific judgment.

1 investor

Syntropy is an autonomous coding agent that generates tested code implementations from feature descriptions and submits pull requests, with integrations for Slack notifications and custom MCP extensions.

1 investor

Talking Computers uses AI-driven agents to optimize machine learning training and inference infrastructure, working across multi-week engagements to run parallel experiments and improve performance on customer workloads, including GPU kernel acceleration and model latency.

1 investor

Tepali provides an AI operating system for medspa businesses. The platform is designed to serve medspa operators.

1 investor

Terminal Use is an applied research lab building agentic systems to operate enterprises.

1 investor

A uranium exploration company using machine learning trained on historical geologic and exploration data to locate high-grade uranium deposits across North America for nuclear fuel supply.

1 investor

The Token Company builds a compression model called Bear-2 that reduces the size of LLM inputs such as documents, websites, and transcripts before they enter an LLM context window. The product enables developers and AI applications to pass more context with fewer tokens to language models.

3 investors

Traverse produces training data for frontier AI models to develop judgment and reasoning in ambiguous, non-deterministic tasks like law, healthcare, and strategic decision-making. The company partners with AI labs to capture real expert reasoning patterns that enable models to perform complex white-collar work at superhuman levels.

2 investors

Travo provides a database of real estate information, including property details, ownership records, zoning restrictions, and financial data, serving investors, developers, and brokers in the real estate industry.

1 investor

Unifold provides multi-chain deposit and payment infrastructure for consumer applications, enabling deposits and payouts of crypto and stablecoins across multiple blockchains through a single API. The platform serves fintech apps, DeFi protocols, prediction markets, and trading platforms with integrated compliance, routing, and settlement capabilities.

2 investors

Unisson provides AI agents that execute customer tasks directly within product interfaces by maintaining an up-to-date knowledge base of product features and workflows. The platform enables businesses to deploy autonomous agents that can perform work across customer-facing products in minutes.

1 investor

Valence provides a trading terminal that unifies execution across prediction markets including Kalshi and Polymarket, routing orders intelligently across multiple venues to achieve optimal pricing. The platform serves traders and liquidity providers with real-time market data, customizable workspace, and risk management infrastructure.

1 investor

Valgo builds risk quantification and safety validation tools for autonomous systems and physical AI, including methodologies for computing crash-rate baselines, failure probability estimation, and scenario generation for robotaxis and autonomous vehicles.

3 investors

Vector Legal provides an AI-powered legal platform combined with expert counsel to deliver end-to-end legal solutions for early-stage companies. The service is designed specifically for startups.

1 investor

Vela is an AI scheduling assistant that automates meeting coordination and calendar management. It handles email back-and-forth, timezone coordination, conflict detection, and rescheduling across teams and stakeholders.

1 investor

Velum develops domain ontologies and semantic infrastructure for enterprise AI using hypergraph technology. It helps organizations structure and enforce data contracts across modern data mesh architectures.

1 investor

Ventura automates quote generation and order processing for sales teams by extracting information from emails, images, and call transcripts, then pushing structured data directly to ERPs and CRMs. The platform serves B2B sales organizations looking to reduce manual data entry and accelerate deal closure.

1 investor

Verdex uses satellite imagery and other data streams to verify insurance claims for agricultural properties, helping insurers process claims faster and reduce costs. The company currently serves insurers covering over 11% of American farmland.

1 investor

Visibl Semiconductors handles end-to-end custom chip design, verification, and manufacturing for hardware companies in robotics, drones, industrial, and IoT sectors that cannot afford traditional semiconductor development costs.

1 investor

Voltair Labs develops autonomous aircraft equipped with visual, thermal, and LiDAR sensors for inspecting and monitoring utility infrastructure, including power lines and substations. The platform enables utilities to conduct asset inspections, damage assessments, and fault localization at scale.

2 investors

Voxel Energy designs and deploys data centers using modular prefabricated systems with on-site power generation and storage, reducing construction timelines from years to months. The company serves data center operators and compute-intensive businesses seeking rapid deployment and energy independence.

3 investors

VOYGR provides location data infrastructure and place understanding for applications requiring accurate, continuously refreshed location information. The company serves businesses building augmented reality experiences and real-world agent applications.

2 investors

Wayco AI is an AI-powered platform for managing medical-legal cases end-to-end, from intake through patient-provider matching and claim processing. The platform serves medical-legal professionals, insurers, and case management teams seeking to automate case review, coordinate care with specialists, and process claims at scale.

1 investor

Wideframe is an AI-powered desktop application for video editors that automates preparation work by searching, organizing, and sequencing footage from local or cloud storage, then outputs native Adobe Premiere Pro project files. It indexes video libraries by semantic meaning rather than filenames and enables editors to describe desired edits in natural language.

1 investor