Y Combinator Summer 2021 (S21) Companies

Dots is an end-to-end payouts platform that enables companies to pay and track payments globally across 190+ countries through 300+ payment rails, including bank transfers, mobile money, and digital wallets. The platform provides API-first integration with compliance features such as identity verification, sanctions screening, and automated tax form collection and filing.

1 investor

Double is a practice management platform that automates accounting workflows including month-end close, tax preparation, and financial reporting for bookkeeping and accounting firms globally.

2 investors

Echoes HQ provides software that helps engineering leaders track how their teams' work aligns with business objectives and measure the business impact of technical deliverables. The platform enables engineers to connect their daily contributions to broader business goals, giving leadership the visibility needed for hiring decisions, team communication, and resource prioritization.

2 investors

Encuadrado is a practice management and payment platform for healthcare professionals and clinics in Chile, offering appointment scheduling, automated invoicing, and integrated payment processing. The platform serves individual practitioners and multi-disciplinary medical centers seeking to streamline administrative operations and financial management.

1 investor

Endla develops engineering design tools that optimize performance and efficiency, with a focus on coal seam gas applications. The company builds AlphaSpace, an autodesign tool for coal seam gas companies using open hole slotted liner completions.

2 investors

Enerjazz operates a battery swapping network for commercial electric vehicles in India, providing an alternative refueling infrastructure similar to gasoline stations. The company also offers first-mile and last-mile e-commerce delivery solutions for commercial fleets.

1 investor

Enso is an AI-first data preparation and blending platform that enables data teams to ingest, clean, transform, and analyze structured and unstructured data across multiple sources including databases, files, and APIs. The platform supports both visual and code-based workflows and runs on cloud and desktop environments.

2 investors

Epinoma develops EpiAmp, a methyl-preserving amplification technology to analyze epigenetic changes and methylation patterns for applications in disease detection, drug development, and patient stratification. The company serves research institutions, pharmaceutical companies, and clinical diagnostic organizations in the biotech and healthcare sectors.

1 investor

Epsilon3 provides a software platform for creating, reviewing, and executing operational procedures, serving teams that need to develop and iterate processes at scale.

9 investors

Equipt Health operates a platform that enables healthcare organizations to dispense prescribed medical devices to patients, handling logistics, clinical provider coordination, technical support, and data integration from connected devices; the company initially focuses on sleep apnea treatment through its consumer brand.

1 investor

Evidence is a browser-based IDE for building interactive data dashboards and reports using SQL and markdown, with AI-powered development tools and support for multiple database backends. The platform targets data analysts and developers who need to create publication-quality visualizations and share data products with enterprise-grade security and performance.

2 investors

Evidently is an open-source library for monitoring machine learning models in production, offering 100+ built-in metrics for data quality, model drift detection, and performance tracking. It serves ML teams and data scientists across enterprises and startups who need to monitor models throughout the ML lifecycle.

2 investors

Exa is an AI-powered search API that retrieves high-quality information from the web in real-time, designed for AI agents, developers, and applications that require precise natural-language search capabilities. The company serves developers, AI teams, and applications like Cursor, Cognition, and HubSpot that need semantically intelligent search infrastructure.

8 investors

Examedi provides at-home blood tests and telemedicine consultations available 24/7 in Chile. The platform handles insurance reimbursement for users and offers clinical-quality health services at lower costs than traditional in-clinic visits.

1 investor

FastFarma operates an online pharmacy platform serving Latin American customers, offering price-competitive medications with rapid delivery.

1 investor

Female Invest is an educational platform providing an investment dictionary and learning resources for retail investors, particularly women interested in financial literacy and investing.

3 investors

Ferveret develops advanced cooling technology for data centers and computing infrastructure, using subcooled boiling methods derived from nuclear reactor engineering. The company serves data center operators and AI/HPC infrastructure providers seeking power-efficient cooling solutions.

6 investors

Filadd offers online test-preparation courses for college entrance exams in Chile, Brazil, Argentina, and Colombia, featuring video lessons, live tutoring, and AI-generated study plans tailored to individual students.

1 investor

A marketplace that allows creators to sell face filter designs as NFTs to fans and provides tools for designing augmented reality filters for social media platforms.

1 investor

Fingo is a digital bank offering mobile banking services to young Africans, enabling account opening in under 5 minutes with free peer-to-peer transactions, savings, and financial education. The platform operates across multiple African markets through a partnership with Ecobank and launched first as a digital-only bank in Kenya.

7 investors

FirstIgnite provides AI software that helps universities, hospitals, nonprofits, and foundations identify, engage, and manage partnership opportunities in research funding, philanthropy, and technology licensing. The platform combines AI-powered prospecting, outreach, and data management for mission-driven organizations.

6 investors

FirstQuadrant was an AI-driven sales platform for tech companies that has been sunset following an acquisition by a leading AI technology company.

1 investor

Fitia provides an AI-powered application that generates customized meal plans and tracks nutrition intake, adjusting recommendations based on user progress and dietary preferences to support weight management and muscle development goals.

1 investor

Float finances inventory for consumer brands by paying supplier invoices immediately and deferring repayment until after the goods are sold.

1 investor