Trefoil Therapeutics
San Diego, US · Founded 2016 · Delaware corporation · 8 known investors
Find your way into Trefoil Therapeutics
530 people in our graph can introduce you to the Trefoil Therapeutics team.
Sign up to see every warm intro you have to Trefoil Therapeutics
- Paths you didn't know you had: your email and LinkedIn already hold routes to the Trefoil Therapeutics team. We find them
- 2nd- and 3rd-degree connections: the friend-of-a-friend routes you can't see from your own inbox or LinkedIn
- Answers now, not in days: momentum is everything in a raise. Skip asking around whether someone knows someone
Days of research, done the moment you sign in, with every route ranked by how warm it is.
Trefoil Therapeutics is a clinical-stage biotechnology company developing therapeutic agents for corneal diseases. Its lead investigational candidate, TTHX1114, is being studied in a Phase 2 trial for improving visual recovery after Descemet Stripping Only (DSO) procedures.
Founders & leadership
Trefoil Therapeutics was founded in 2016 by David Eveleth.


Board

Investors · 8
How we know: ExSight Ventures's portfolio page · the company's own site · open dataset · 5k.vc investor directory · Not right? Tell us
How we know: the company's own site · a partner's Signal profile · funding news · the VCSheet dataset · Not right? Tell us
How we know: the company's own site · open dataset · 5k.vc investor directory · Not right? Tell us
How we know: the company's own site · funding news · Not right? Tell us
How we know: the company's own site · board seat on SEC Form D · funding news · Not right? Tell us
How we know: the company's own site · Not right? Tell us
Funding
SEC filings, press & company announcements$33.3M disclosed across 4 of 5 rounds · 2016–2025
- Undisclosed amountSeries ADec 2021Source ↗
▶$4.6MraisedMay 2025 · 16 investors · BiotechnologyRule 506(b)
- Christy ShafferDirector
- Stella RobertsonDirector
- Jonathan MowExecutive Officer
- Ben McGrawDirector
- John FucciDirector
- Kseniya SimpsonDirector
- Offering amount
- $5M
- Amount sold
- $4.6M
- First sale
- Apr 2025
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$12MraisedMar 2022 · 14 investors · BiotechnologyRule 506(b)
- Christy ShafferDirector
- Derek YoonDirector
- Stella RobertsonDirector
- Ben McGrawDirector
- David EvelethExecutive Officer, Director
- Schalon NewtonExecutive Officer
- Offering amount
- $12M
- Amount sold
- $12M
- First sale
- Mar 2022
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$12.6MraisedAug 2019 · 13 investors · BiotechnologyRule 506(b)
- Christy ShafferDirector
- Derek YoonDirector
- Stella RobertsonDirector
- Schalon NewtonExecutive Officer
- David EvelethExecutive Officer, Director
- Ben McGrawDirector
- Offering amount
- $28M
- Amount sold
- $12.6M
- First sale
- Jul 2019
- Incorporated
- Corporation, Delaware, 2016
- Federal exemptions
- 06b
▶$4.2MraisedDec 2016 · 14 investors · BiotechnologyRule 506(b)
- Ralph BradshawDirector
- Christy ShafferDirector
- Schalon NewtonExecutive Officer
- David EvelethExecutive Officer, Director
- Offering amount
- $5.2M
- Amount sold
- $4.2M
- First sale
- Dec 2016
- Incorporated
- Corporation, Delaware, 2016
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Related companies · 1
Companies working in the same space as Trefoil Therapeutics.
In the news
Frequently asked questions
- What does Trefoil Therapeutics do?
- Trefoil Therapeutics is a clinical-stage biotechnology company developing therapeutic agents for corneal diseases. Its lead investigational candidate, TTHX1114, is being studied in a Phase 2 trial for improving visual recovery after Descemet Stripping Only (DSO) procedures.
- Who founded Trefoil Therapeutics?
- Trefoil Therapeutics was founded by David Eveleth in 2016.
- Who are Trefoil Therapeutics's investors?
- Trefoil Therapeutics's investors include ExSight Ventures, Hatteras Venture Partners, Solasta Ventures, Access Biotechnology, Bios Partners, Correlation Ventures, FemHealth Ventures, InFocus Capital Partners, LLC.
- How much funding has Trefoil Therapeutics raised?
- Trefoil Therapeutics has disclosed $33.3M raised across 4 of its 5 known rounds.
- Where is Trefoil Therapeutics headquartered?
- Trefoil Therapeutics is headquartered in San Diego, US.





