Simplex
YC S24San Francisco, US · Founded 2024 · 2 employees · 4 known investors
Simplex provides automated provider enrollment management for healthcare networks, handling CAQH profile setup, payer applications, and compliance tracking across multiple states and insurers. The platform uses AI agents to submit applications, monitor status, fix corrections, and deliver final enrollment determinations with full audit trails.
Also known as Pansimulate
AI & Machine LearningDeveloper ToolsEnterprise SoftwareHealthtechMachine LearningRobotic Process AutomationB2BAIUnited States of AmericaAmerica / Canada
Founders & leadership· Y Combinator alumni (S24)
Simplex was founded in 2024 by Shreya Karpoor and Marco Nocito.
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Shreya KarpoorinCo-founder and CEOShe holds degrees in electrical engineering and computer science from MIT and has prior experience in software development at Tesla and robotics research at MIT.
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Marco NocitoinCo-founder and CTOMarco Nocito holds degrees in Computer Science from MIT and has prior experience building machine learning models at Waymo, developing data infrastructure at Viam, and working at Bloomberg. He is co-founder and CTO of Simplex.
Investors · 4
In the news
Simplex Infrastructures Ltd Upgraded to Hold on Improved Technicals and Financial Trendsmarketsmojo.com · Jul 2026Frequently asked questions
- What does Simplex do?
- Simplex provides automated provider enrollment management for healthcare networks, handling CAQH profile setup, payer applications, and compliance tracking across multiple states and insurers. The platform uses AI agents to submit applications, monitor status, fix corrections, and deliver final enrollment determinations with full audit trails.
- Who founded Simplex?
- Simplex was founded by Shreya Karpoor, Marco Nocito in 2024.
- Who are Simplex's investors?
- Simplex's investors include FundersClub, Sterling Road, Y Combinator, Bitmain.
- Where is Simplex headquartered?
- Simplex is headquartered in San Francisco, US.


