Sepio
Founded 2016 · 76 employees on LinkedIn · 15 known investors
Platform using physical-layer fingerprinting and machine learning plus threat intelligence for hardware infrastructure visibility and enforcement.
Also known as Sepio Systems
Investors · 15
Also in the syndicate · 6
Funding
SEC filings, press & company announcements$22M disclosed across 1 of 3 rounds · 2022–2024
- $22MraisedNov 2022 · 2 sourcesSource ↗
- Undisclosed amountSeries BOct 2022 · 2 sources
U.S. Venture Partners (lead), Bess Ventures, Citi Ventures, Hanaco Ventures, Merlin Ventures, Munich RE Ventures, Pico Partners, Stanford University, World Trade Ventures
Source ↗
Source: company announcements and press reports — follow each round's link for the claim.
Company profile
researched Aug 2026Sepio (also referred to as Sepio Systems) provides a hardware asset risk management platform built on physical-layer device identification. The platform performs continuous asset discovery across networks, endpoints and peripherals, covering IT, OT, IoT and IoMT environments, and identifies devices by their inherent physical characteristics rather than by identifiers such as MAC addresses or VID/PID that can be changed or spoofed. The company markets this capability under the patented AssetDNA name and positions the product as not requiring traffic or activity monitoring, making it, per the company, use-case and device agnostic.
The platform is organized around a framework the company calls Zero Trust Hardware Access (ZTHA), built on five stages: discovery of connected assets; verification of true device identity via physical-layer intelligence; validation against expected role, location, ownership, behavior and policy; risk scoring using identity, posture, vulnerability and business context; and enforcement through alerts, access restriction, isolation, blocking and third-party orchestration. Sepio correlates discovered assets with external vulnerability sources, OSINT and internal cyber research to flag devices that may be exposed, outdated, unsupported or otherwise associated with hardware, firmware or vendor risk. It is offered as a SaaS or on-premises deployment and includes out-of-the-box integrations with third-party cybersecurity and IT tools. In 2024 the company also introduced a managed service offering called Hardware Detection and Response (HWDR)."]
Founding story
Sepio was founded in 2016 by a team whose members began their careers in the Israeli intelligence community in the early 1990s and had built and sold cybersecurity companies together since the late 1990s. Co-founder and CEO Yossi Appleboum served in the Israeli Army Intelligence Corps (Unit 8200), co-founded WebSilicon in 1998 and became its CTO in 2007; WebSilicon was acquired by Magal (NASDAQ: MAGS) in 2013 and rebranded as CyberSeal, after which Appleboum served as CTO for cyber security at Magal's North American division, Senstar, and relocated to the United States. After two prior exits, the founders started Sepio with the aim of protecting organizations against malicious hardware attacks, a threat they viewed as widespread but lacking effective mitigation.
Business model
Sepio sells its hardware asset risk management platform to enterprise and government organizations, delivered either as SaaS or on-premises software, with an accompanying managed service, Hardware Detection and Response (HWDR). Distribution channels referenced include the Microsoft Azure Marketplace, where the company states it is eligible under the Microsoft Azure Consumption Commitment (MACC) program.
Revenue derives from sales of the asset visibility and hardware risk management platform in SaaS or on-premises form, plus a managed service (Hardware Detection and Response), with availability through the Microsoft Azure Marketplace.
Traction
The company reports growing demand from tier-1 enterprises across multiple verticals and territories, cumulative funding of $48 million as of August 2024, and the formation of a Customer Advisory Board of global customers to inform its product roadmap. It has been recognized in Gartner's Cool Vendor awards and by Frost & Sullivan, and earlier reported approval for the U.S. DHS CDM program.
Latest developments
In August 2024 Sepio announced a Series B extension led by Tau Capital, taking total funding to $48 million and funding expansion of customer-facing teams and its Hardware Detection and Response managed service. The company later announced eligibility under the Microsoft Azure Consumption Commitment (MACC), making asset-level visibility available through the Azure Marketplace. Current product messaging centers on the Zero Trust Hardware Access framework and AssetDNA-based hardware identity, vulnerability intelligence and automated enforcement.
▸Full profile — market position, technology, go-to-market, geography, history
Market position
Sepio describes itself as the first hardware asset risk management platform based on device existence and positions itself in the asset risk management and network access control space. Third-party recognition cited in company announcements includes Frost & Sullivan commentary on its innovation and reputation in the network access control market and inclusion in Gartner's annual Cool Vendor awards.
Sepio's stated differentiator is identification of assets at the physical layer, in contrast to approaches relying on MAC addresses, VID/PID values or network traffic analysis, which the company says can be spoofed or misled. Because the solution does not require traffic or activity monitoring, the company describes it as use-case and device agnostic, and it claims customers can see, assess and mitigate asset risk within less than 24 hours at any scale.
Technology
The core technology is AssetDNA, a patented method of identifying hardware assets by inherent physical-layer characteristics rather than by mutable software identifiers, creating a hardware-level identity for each device to detect rogue, impersonating, unauthorized and unmanaged assets. The approach does not depend on traffic or activity monitoring. Discovered assets are correlated with external vulnerability feeds, OSINT and in-house cyber research to support risk scoring, and policy-driven automation can isolate, block, alert on or restrict devices in real time, including through integrations with third-party security and IT products. The company has also described machine learning as part of its capabilities, with a dedicated machine learning R&D center.
Go-to-market
Direct enterprise sales supported by customer-facing organizations that the 2024 funding was intended to expand, alongside a managed service offering and cloud marketplace availability via Microsoft Azure. The company has established a Customer Advisory Board to gather customer feedback on its product roadmap, and its founders have cited approval for the U.S. Department of Homeland Security's Continuous Diagnostics and Mitigation (CDM) program as a route into government accounts. Executives also participate in industry events such as the Cybersecurity Summit.
Enterprise and public-sector organizations with large or complex connected-asset environments spanning IT, OT, IoT and IoMT. Frost & Sullivan, as quoted in the company's funding announcement, cites government agencies, financial institutions, critical infrastructure, managed security service providers, healthcare, manufacturing and retail as relevant segments; the company describes demand from tier-1 global enterprises across multiple verticals and territories.
Geography
Global headquarters in Rockville, Maryland, United States, with R&D centers in Tel Aviv, Israel, and Lisbon, Portugal as reported in 2020. The company describes customers across multiple territories.
History
Founded in 2016 and headquartered in Rockville, Maryland, Sepio operated R&D centers in Tel Aviv, Israel (core) and Lisbon, Portugal (machine learning) as of 2020, when the company reported approval for the U.S. DHS CDM program. Appleboum was described as Co-CEO in 2016-era materials and as CEO by 2024. In August 2024 the company announced an extension of its Series B round led by Abu Dhabi-based Tau Capital, bringing total funds raised to $48 million, with proceeds directed toward customer-facing teams and its newly introduced HWDR managed service. The company subsequently announced eligibility under the Microsoft Azure Consumption Commitment, offering asset-level visibility via the Azure Marketplace.
Compiled by commissioned research from 6 cited public sources — announcements, filings, and press listed under research sources below.
Key figures
latest reportedCompany-reported or press-reported figures, each dated to when it was claimed — not independently audited.
Timeline · 5
launches, deals, and filingsCompany funding announcement cites Gartner's annual Cool Vendor awards praising Sepio for providing visibility into assets on networks and connected to endpoints.
Sepio announced a new investment extending its Series B funding, led by Abu Dhabi-based Tau Capital, to expand customer-facing organizations and resource its Hardware Detection and Response (HWDR) managed service. Total funds raised reached $48 million. Prior investors listed include U.S. Venture Partners (USVP), Hanaco Ventures, Munich RE Ventures, Merlin Ventures, Citi Ventures, Pico Partners and Stanford University, plus additional private investors.
Sepio announced eligibility under the Microsoft Azure Consumption Commitment, offering asset-level visibility via the Azure Marketplace.
Sepio described HWDR as a recently introduced managed service, toward which part of the 2024 Series B extension was allocated.
In a 2020 interview, CEO Yossi Appleboum said Sepio had recently been approved by the U.S. Department of Homeland Security for its CDM program.
Dated company events from announcements, filings, and press; legal rows summarize public dockets and regulator releases.
In the news
▸Research sources · 6
primary sources listed
- Cyber Risk Management Platform & Physical Layer Visibility | Sepiosepiocyber.com · web
6 public sources were cited for this profile; the first-party ones are listed here.
Frequently asked questions
- What does Sepio do?
- Sepio is a hardware asset risk management vendor using physical-layer device fingerprinting for asset visibility and enforcement.
- Who are Sepio's investors?
- Sepio's investors include Beacon VC, Hanaco Venture Capital, Mindset Venture, US Venture Partners, World Trade Ventures (WTV), Citi Ventures, Merlin Ventures, Stanford University and 1 more.
- How much funding has Sepio raised?
- Sepio has disclosed $22M raised across 1 of its 3 known rounds.


