/Companies

Primmune Therapeutics

Carlsbad, US · Founded 2017 · 9 employees on LinkedIn · 6 known investors

Find your way into Primmune Therapeutics

6 people in our graph share verified history with the Primmune Therapeutics team — schools, employers, funds. One of them is your warm intro.

Luke Hortonunlockedknows Paulo Rangel · together at Besins Healthcare (overlapped)
knows the team · via Evince Biosciences
×3knows the team · via Primmune Therapeutics
knows the team · via Besins Healthcare

Primmune Therapeutics develops PRTX007, an orally administered, systemically active TLR7 agonist that activates interferon-associated innate immune pathways for use in cancer immunotherapy. The candidate is being developed for oncology applications, including combination with immune checkpoint inhibitors and neoadjuvant/adjuvant settings, and has been tested in two Phase 1 studies in healthy volunteers.

Founders & leadership

Primmune Therapeutics was founded in 2017 by James Appleman, Paulo Rangel, and Stephen Webber.

JAJames Appleman
James ApplemanSVP, R&D and CSO, Cofounder
PRPaulo Rangel
Paulo RangelChief Business Officer and CofounderHe brings experience in pharmaceutical and medical device business development, including licensing, valuations, clinical trials, and intellectual property management, and holds an MBA from Duke University and a BA in Chemistry/Biochemistry from UC San Diego.
SW
Stephen WebberVice President, Medicinal Chemistry, and Cofounder
CMCharles McDermott
Charles McDermottPresident & CEO, Director

Board

TJTodd J Harris
Todd J HarrisMember of the Board of Directors2017–2024Director, Executive Officer at Sienna Biopharmaceuticals

Investors · 6

Funding

SEC filings, press & company announcements

$20.1M disclosed across 5 of 7 rounds · 2017–2026

  • Undisclosed amountSeries BJan 2026 · 2 sources
    Source ↗
▶$13MraisedNov 2020 · 12 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Charles McDermottExecutive Officer, Director
  • James R. ApplemanExecutive Officer, Director
  • Todd J. HarrisDirector
  • Paulo S. RangelExecutive Officer
  • Scott MorensteinDirector
  • Andrew RubinsteinDirector
  • Amir NashatDirector
Offering amount
$24M
Amount sold
$13M
First sale
Oct 2020
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$1.1MraisedMar 2020 · 19 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Charles McDermottExecutive Officer, Director
  • James R. ApplemanExecutive Officer, Director
  • Todd J. HarrisDirector
  • Paulo S. RangelExecutive Officer, Director
  • Scott MorensteinDirector
Offering amount
$4M
Amount sold
$1.1M
First sale
Jul 2018
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$2MraisedMar 2020 · 17 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Charles McDermottExecutive Officer, Director
  • James R. ApplemanExecutive Officer, Director
  • Todd J. HarrisDirector
  • Paulo S. RangelExecutive Officer, Director
  • Scott MorensteinDirector
Offering amount
$4M
Amount sold
$2M
First sale
Feb 2019
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$2.5MraisedMar 2020 · 2 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Charles McDermottExecutive Officer, Director
  • James R. ApplemanExecutive Officer, Director
  • Todd J. HarrisDirector
  • Paulo S. RangelExecutive Officer, Director
  • Scott MorensteinDirector
Offering amount
$3.5M
Amount sold
$2.5M
First sale
Feb 2020
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$1.5MraisedJan 2018 · 36 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • Todd J HarrisDirector
  • Paulo S RangelExecutive Officer, Director
  • James R ApplemanExecutive Officer, Director
Offering amount
$1.5M
Amount sold
$1.5M
Proceeds to insiders
$360K
First sale
Oct 2017
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

In the news

Frequently asked questions

What does Primmune Therapeutics do?
Primmune Therapeutics develops PRTX007, an orally administered, systemically active TLR7 agonist that activates interferon-associated innate immune pathways for use in cancer immunotherapy. The candidate is being developed for oncology applications, including combination with immune checkpoint inhibitors and neoadjuvant/adjuvant settings, and has been tested in two Phase 1 studies in healthy volunteers.
Who founded Primmune Therapeutics?
Primmune Therapeutics was founded by James Appleman, Paulo Rangel, Stephen Webber in 2017.
Who are Primmune Therapeutics's investors?
Primmune Therapeutics's investors include BioBrit, BioRock Ventures, Samsara BioCapital, Bioqube Ventures, Oberland Capital, Polaris Partners.
How much funding has Primmune Therapeutics raised?
Primmune Therapeutics has disclosed $20.1M raised across 5 of its 7 known rounds.
Where is Primmune Therapeutics headquartered?
Primmune Therapeutics is headquartered in Carlsbad, US.