Ophirex
Corte Madera, US · Delaware corporation · 2 known investors
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Ophirex is a biotech company developing varespladib, an investigational oral capsule intended to treat snakebite envenomation by inactivating a key venom toxin found in most snake species. The drug is designed as a portable, field-administered rescue treatment to bridge the gap before hospital antivenom.
Founders & leadership
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Investors · 2
How we know: a partner's Signal profile · Not right? Tell us
Funding
SEC filings, press & company announcements$16.5M disclosed across 1 of 3 rounds · 2019–2023
- Undisclosed amountSeries BJan 2023Source ↗
▶$16.5MraisedMar 2022 · 18 investors · OtherRule 506(b)
- Jeremiah HarrisonDirector
- Derrick RossiDirector
- Curt LaBelleDirector
- Hans BishopDirector
- Timothy GarnettDirector
- Nancy J. KochExecutive Officer, Director
- Matthew R. LewinDirector
- Offering amount
- $35M
- Amount sold
- $16.5M
- First sale
- Mar 2022
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$5MofferedMar 2019 · OtherRule 506(b)
- Jerry HarrisonDirector, Promoter
- Matthew LewinExecutive Officer, Director, Promoter
- Howard PienDirector, Promoter
- Nancy J. KochExecutive Officer, Director, Promoter
- Offering amount
- $5M
- Minimum investment
- $5K
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Related companies · 2
Companies working in the same space as Ophirex.
Non-dilutive funding · 3 SBIR/STTR awards
Federal grants — no equity taken| Agency | Phase | Year | Amount |
|---|---|---|---|
| Department of DefenseDefense Health Program | Phase II | 2023 | $1.3M |
| Department of DefenseDefense Health Program | Phase II | 2021 | $1.5M |
| Department of DefenseDefense Health Program | Phase I | 2018 | $148.5K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.
In the news
Frequently asked questions
- What does Ophirex do?
- Ophirex is a biotech company developing varespladib, an investigational oral capsule intended to treat snakebite envenomation by inactivating a key venom toxin found in most snake species. The drug is designed as a portable, field-administered rescue treatment to bridge the gap before hospital antivenom.
- Who founded Ophirex?
- Ophirex was founded by Jerry Harrison, Matthew R. Lewin.
- Who are Ophirex's investors?
- Ophirex's investors include Global Health Investment Fund, Tullis Health Investors.
- How much funding has Ophirex raised?
- Ophirex has disclosed $16.5M raised across 1 of its 3 known rounds.
- Where is Ophirex headquartered?
- Ophirex is headquartered in Corte Madera, US.

