Curistrelief

Curist is a consumer healthcare brand that sells over-the-counter medications directly to US consumers through its own online store. Its catalog covers allergy relief (levocetirizine, loratadine, cetirizine, fexofenadine, including a children's chewable), heartburn and acid reflux (esomeprazole, omeprazole, famotidine), mucus and cold/flu products (guaifenesin), lidocaine creams, patches and sprays, arthritis relief (diclofenac gel 1%), gas relief (simethicone), acne treatment (adapalene gel 0.1%), antifungal treatment (terbinafine cream 1%) and hemorrhoid relief. Products are positioned against national brand equivalents such as Xyzal, Claritin, Zyrtec, Allegra, Nexium, Prilosec OTC, Pepcid AC, Mucinex, Voltaren and LamisilAT, at prices typically ranging from roughly $10 to $40 per pack.

The company's registered corporate entity is Little Pharma, Inc., an American company based in New York City; Curist is a registered trademark of that entity and all products are distributed by it. Its stated mission is to increase access to affordable medication and improve self-treatment of symptoms, which it pursues through product donations, new product launches and published health articles. A panel of clinical advisors is associated with the brand, including Dr. Marc Goldstein, MD, described as Curist Chief Medical Advisor and Allergy Chief at Pennsylvania Hospital, and Dr. Waverly Yang, PharmD, faculty at the Massachusetts College of Pharmacy.

Curist medicines are produced in manufacturing facilities in the United States and abroad, including Canada and India. All products are available without a prescription and are HSA- and FSA-eligible, with HSA/FSA card payments processed through the Sika payment gateway.

Founding story

Founder Ethan, who has severe allergies and asthma and whose father is an allergy physician, grew up with household discussions about medicine, allergies and the difficulty of self-treating at home. He started the company in 2018 to simplify the pharmacy aisle, beginning with allergy products.

Business model

Curist operates an online direct-to-consumer model under the corporate entity Little Pharma, Inc., working directly with manufacturing facilities and selling to consumers online in order to bypass distribution middlemen and brand-name markups, which it describes as ranging from 200% to 3,000%. Products are also sold through third-party marketplaces including Amazon.com and Walmart.com, where the company's own return terms do not apply.

Revenue comes from product sales of over-the-counter medicines, offered as either one-time purchases or recurring subscription orders. Orders over $35 ship free, and subscription orders are payable only by credit card. Accepted payment methods include major credit cards, PayPal, Amazon Pay, Google Pay and Shopify Pay, plus HSA/FSA debit cards.

Traction

Third-party profiles describe a team of roughly 2-10 employees (approximately 6 as of July 2026) based in North America, with estimated annual revenue in the $25M-$50M range; the company also states it is hiring.

Latest developments

The company relocated its New York corporate address in October 2025 and continues to expand its product range, with a website sign-up for forthcoming products.