James Orsillo
InvestorPartner at Underscore VC
Boston, Massachusetts
Writes $1M – $5M checks · typically $2.5M
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About
James Orsillo is a General Partner at Underscore VC and serves as CFO of Underscore-backed TetraScience. He has spent his career in finance and operating roles, having previously been CFO at Maxwell Health and Evariant, where he led venture financings and scaled finance and operations teams that ended in exits for both companies. Earlier in his career he held finance and operating roles at American Tower, Kaz (now Helen of Troy), Decision Resources Group, Digitas, and State Street, and over his career has been involved in more than $2.5B in equity and debt transactions. At Underscore, he advises or sits on the boards of more than a dozen portfolio companies and is among the leaders who assumed management of the firm's General Partnership.
Contact· published on James's own website
Beyond investing
- Education
- Earned a Master of Science in Finance from Brandeis University. Earned a Bachelor of Science from Boston College.
- Awards
- Holds the Chartered Financial Analyst designation from the CFA Institute.
- More
- Has worked since age 12 in a wide range of jobs including paper boy, landscaper, pizza dough maker, library operator, perfume salesperson, courthouse sheriff, and legal office admin assistant. Is known internally at Underscore as 'The Wolf' (or 'Wolfman'), a nod to the fixer from Pulp Fiction. Has advised or served as a board Director for well over a dozen Underscore portfolio companies.
From James's own website — common ground for a warm intro.
Investments
Board seats
Per SEC Form D filings.
Colleagues at Underscore VC
Network2
Investors connected to James in public investor directories — a warm-intro map.
Frequently asked questions
- Who is James Orsillo?
- James Orsillo is a General Partner at Underscore VC and serves as CFO of Underscore-backed TetraScience. He has spent his career in finance and operating roles, having previously been CFO at Maxwell Health and Evariant, where he led venture financings and scaled finance and operations teams that ended in exits for both companies. Earlier in his career he held finance and operating roles at American Tower, Kaz (now Helen of Troy), Decision Resources Group, Digitas, and State Street, and over his career has been involved in more than $2.5B in equity and debt transactions. At Underscore, he advises or sits on the boards of more than a dozen portfolio companies and is among the leaders who assumed management of the firm's General Partnership.
- Where does James Orsillo work?
- James Orsillo is Partner at Underscore VC.
- What check size does James Orsillo write?
- James Orsillo typically writes checks of $1M – $5M.
- What boards does James Orsillo sit on?
- James Orsillo holds tracked board seats at CloudZero.
- What awards has James Orsillo received?
- Holds the Chartered Financial Analyst designation from the CFA Institute.
About this profile. Compiled from public sources — Underscore VC's own website and public professional profiles — and summarised by Fundraising Fox; every fact is kept with where it came from. Spotted an error, or would rather not be listed? Email privacy@fundraisingfox.com · How we build profiles · Your rights








