Fundraising Fox

James Orsillo

Investor

Partner at Underscore VC · Board director at TetraScience · Board director at CloudZero

Boston, Massachusetts

Writes $1M – $5M checks · typically $2.5M

About

James Orsillo is the CFO at Underscore-backed TetraScience and previously served as CFO at Maxwell Health and Evariant, where he led venture financing rounds and built finance and operations teams that resulted in exits for both companies. Earlier in his career he held finance and operating roles at American Tower, Kaz (now Helen of Troy), Decision Resources Group, Digitas, and State Street. He holds a Master of Science in Finance from Brandeis University, a Bachelor of Science from Boston College, and the CFA designation.

Contact· published on James's own website

Board director at TetraScienceYC S15

Intro paths

YC

James went through Y Combinator (Summer 2015) — any YC alum in your network can reach them through the YC community.

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In turn, James can intro founders to TetraScience's investors below.

TetraScience's investors · 8

Alkeon InnovationNew YorkDorm RoomBrooklyn · $90K – $250K checksFloodgateMenlo Park · $500K – $5M checksFounder CollectiveCambridgeInsight PartnersNew York · $120M – $350M checksKarlin VenturesLos Angeles · $250K – $2M checksUnderscore VCBoston · since 2021Y CombinatorSan Francisco · $500K checks · since 2015

Co-founders at TetraScience

SWSiping Wang
Siping WangFounder/CTO
SS
Salvatore SavoDirector, Executive Officer

Board director at CloudZero

Intro paths

→

In turn, James can intro founders to CloudZero's investors below.

CloudZero's investors · 5

G20 VenturesCambridge · $2M – $5M checksInnovius CapitalSan FranciscoMatrixSan Francisco · $100K – $10M checks · since 2025Threshold VenturesPalo Alto · $500K – $20M checksUnderscore VCBoston · since 2020

Co-founders at CloudZero

EPErik Peterson
Erik PetersonExecutive Officer, Director
MMMatt Manger
Matt MangerFounder

Experience

  1. TetraScienceChief Financial Officercurrent2026 — presentBoston, MA
  2. TetraScienceBoard Director2021 — 2026Boston, MA
  3. Underscore VCVenture Partnercurrent2026 — presentBoston, MA
  4. Underscore VCGeneral Partner, CFO/O2021 — 2026Boston, MA
  5. Underscore VCCFO/O2018 — 2021Boston, Massachusetts
  6. SalsifyBoard Directorcurrent2024 — presentBoston, Massachusetts, United States
  7. ApploiBoard Director2023 — 2026New York, United States
  8. CloudZeroBoard Director2023 — 2026Boston, MA
  9. SaaS Metrics Standards BoardAdvisory Council Membercurrent2023 — present
  10. OPEXEngineAdvisory Board Member2016 — 2020Greater Boston
  11. Maxwell HealthChief Financial Officer2016 — 2018Boston, Massachusetts
  12. Evariant, a Healthgrades companyChief Financial Officer2012 — 2016Farmington, CT
  13. American TowerSenior Manager, Corporate FP&A2010 — 2011Boston, MA
  14. Kaz USA, Inc. a Helen of Troy CompanyBusiness Partner, Finance2007 — 2010
  15. Decision Resources Group, part of ClarivateManager, FP&A2002 — 2007
  16. DigitasSenior Financial Analyst2000 — 2001
  17. DeltaTrendsFinance and Operations Manager1999 — 2000Boston, Massachusetts, United States

Skills & more

Strategy66Strategic Planning32Management44Leadership56Analysis22Forecasting50Finance47Project Planning9Financial Analysis21Financial Modeling15Financial Reporting17Budgets15
+12 moreBusiness ProcessAccountingRisk ManagementProject ManagementStrategic Financial PlanningCorporate FinanceBusiness StrategyCompetitive AnalysisSaaSSoftware as a Service (SaaS)AnalyticsNew Business Development
  • Chartered Financial Analyst — 162977

From James's professional profile.

Investments

Board seats

CloudZero

Per SEC Form D filings.

Colleagues at Underscore VC

Andrew Palmer
Co-Founder of Tamr at Underscore VC
Brian Devaney
Partner at Underscore VC
Brian Fakhoury
Investment Analyst at Underscore VC
Chris Gardner
Partner at Underscore VC
Claire Crowther
Vice President, Strategy & Operations at Underscore VC
Corey Thomas
Chairman & CEO of Rapid7 at Underscore VC
Devin Nash
Vice President, Brand & Experience at Underscore VC
Dries Buytaert
Founder of Acquia & Drupal at Underscore VC

Network2

Brian Devaney
Partner at Underscore VC
Chris Gardner
Partner at Underscore VC

Investors connected to James in public investor directories — a warm-intro map.

Frequently asked questions

Who is James Orsillo?
James Orsillo is the CFO at Underscore-backed TetraScience and previously served as CFO at Maxwell Health and Evariant, where he led venture financing rounds and built finance and operations teams that resulted in exits for both companies. Earlier in his career he held finance and operating roles at American Tower, Kaz (now Helen of Troy), Decision Resources Group, Digitas, and State Street. He holds a Master of Science in Finance from Brandeis University, a Bachelor of Science from Boston College, and the CFA designation.
Where does James Orsillo work?
James Orsillo is Partner at Underscore VC and Board director at TetraScience and Board director at CloudZero.
What check size does James Orsillo write?
James Orsillo typically writes checks of $1M – $5M.
What boards does James Orsillo sit on?
James Orsillo holds tracked board seats at CloudZero.
Where did James Orsillo go to school?
James Orsillo studied at CFA Institute (Charterholder); Brandeis School of Business and Economics (MSF, Finance - Concentration); Boston College (BS, Business Administration).

Same school

Also attended CFA Institute336

Matt CherianVenture Partner at Monta Vista CapitalLaviva MazharPrincipal at Luge CapitalJan AvontsInvestment Director at Capricorn Venture PartnersMatias BarberoVenture Partner at FJ LabsKim RobertsonFinancial Manager at 4Di CapitalCole LundquistPrincipal at QED Investors

+ 330 more

Also attended Brandeis School of Business and Economics6

Masha LevinVenture Partner at One Way VenturesNoemi HipperInvestment Managerin at YabeoErtunc AliogluCFO at Bek VenturesRodolphe MenegauxPartner at AlvenMarcus ErkenPartner at Sunfish PartnersVlad LukashevskyInvestor at TENFORE HOLDINGS

Also attended Boston College196

Pat GradyPartner at Sequoia CapitalDavid FialkowGeneral Catalyst co-founder, founder-first company builder, data and digital-health investor, and documentary producerNicole GaudelliEntrepreneur in Residence at GV (Google Ventures)Bijan SabetPersonal journalSteve MurrayAdvisor, Revolution Growth at RevolutionNatalie SchmitkeManaging Director Capital Networks at Burda Principal Investments

+ 190 more

Shared employers

Also worked at Underscore VC25

Lily LymanPartner at Underscore VCChris GardnerPartner at Underscore VCBrian DevaneyPartner at Underscore VCGabrielle McCarthySenior Investment Associate at Underscore VCDevin NashVice President, Brand & Experience at Underscore VCClaire CrowtherVice President, Strategy & Operations at Underscore VC

+ 19 more

Also worked at Salsify3

Michael KruszynskiOperating Partner at eGateway CapitalMichael SkokPartner Emeritus at Underscore VCReid ChristianGeneral Partner at CRV (Charles River Ventures)

Also worked at Maxwell Health1

Ron BouganimManaging Partner at Govtech Fund

Also worked at Decision Resources Group, part of Clarivate8

Brigham HydeVenture Partner at Audere CapitalSuraj NairAssistant Vice President at Ankur CapitalPhillip SamayoaPrincipal at Atlas VentureGilan MegeedPrincipal at Deerfield Management CompanyLily KimPartner at OS FundJulie CurranVenture Partner at Techstart Ventures

+ 2 more