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PFM Health Sciences

Crossover fund

San Francisco · Pre-Seed–Series A · 2 people tracked

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Investment thesis

PFM Health Sciences focuses on the healthcare sector, believing the industry is in a powerful, long-term innovation cycle producing transformative investment opportunities. The firm takes a specialist, bottom-up, fundamental approach, leveraging secular growth, domain expertise, and demographic trends. It values partnering with companies that deliver measurable and sustainable impact on health outcomes while being responsible stewards of institutional capital. Risk management and portfolio construction aim to dampen volatility while offering an attractive return-to-risk profile. The firm emphasizes flexibility to invest across the capital structure in both public and private companies within biopharma, medical technology, life science, and healthcare services.

Source: firm website, verified Aug 16, 2026.

Stage
Pre-Seed–Series A
HQ
San Francisco, California, US
Instruments
Equity
Founded
2004

Team · 2 people

from the firm's website & public directories
Brian Grossman· Founding Partner and CIO

Founding Partner and Chief Investment Officer who leads PFM Health Sciences.

Frequently asked questions

What stage does PFM Health Sciences invest at?
PFM Health Sciences invests at the Pre-Seed, Seed, Series A stages.
What sectors does PFM Health Sciences focus on?
PFM Health Sciences focuses on AI & Machine Learning, Biotech, Consumer, Crypto & Web3, Digital Health, Fintech, Healthtech, Medical Devices, SaaS.
Where is PFM Health Sciences located?
PFM Health Sciences is headquartered in San Francisco, US.

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