Zeph
Techstars '24AntlerNew York City, US · Founded 2023 · 13 employees on LinkedIn · 2 known investors
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Zeph develops a digital health platform with clinical-grade sensors to help patients manage respiratory conditions like COPD through home-based rehabilitation and evidence-based exercises. The platform serves patients, clinicians, and care teams seeking better respiratory health management.
Also known as Zeph Technologies
Founders & leadership
Zeph was founded in 2023 by Shikha Anand, MD, MPH, Mimi Gendreau Kigawa, and Francis Kigawa.


Investors · 2
How we know: open dataset · Top 3000 Accelerator Startups (no YC) 2026-08 · open dataset · 5k.vc investor directory · Not right? Tell us
How we know: the Techstars portfolio · open dataset · Top 3000 Accelerator Startups (no YC) 2026-08 · open dataset · 5k.vc investor directory · Not right? Tell us
Company profile
researched Sep 2026Zeph (Zeph Technologies) is a virtual pulmonary platform that enables clinical teams to deliver pulmonary rehabilitation and longitudinal respiratory care to patients at home. Its core offering is an eight-week virtual pulmonary rehabilitation program comprising more than 25 education modules, a library of over 100 breathing, balance, flexibility and strength exercises, and 10 assessments covering physical health, mental health and quality of life. The program is delivered through a telemedicine environment purpose-built for group pulmonary rehabilitation video visits with embedded content and exercise demonstrations, followed by an asynchronous "Maintenance Mode" for ongoing exercise and education.
Patients receive a "Zeph Kit" containing a pre-configured tablet and basic exercise equipment at no charge, plus 1:1 onboarding sessions; a stable WiFi connection is preferred but described as not strictly required, and support is available to patients and clinicians around the clock. Safety monitoring uses FDA-approved Bluetooth-connected continuous heart rate and SpO2 devices, with real-time two-way audiovisual supervision during sessions and patient training on the RPE scale to avoid overexertion. Zeph reports outcomes on adherence and retention, quality of life, functional capacity, dyspnea and mental health.
The company also markets the Zeph Trainer, a portable smart breath-training device with respiratory sensors, a rechargeable USB-C battery and wireless sync to the Zeph app on iOS and Android. The app converts respiratory data into a breathability score, guided exercises and progress tracking over time, and supports sharing data with a patient's care team for remote monitoring between office visits. The boxed product includes the trainer, USB-C cable, carrying case, quick start guide and a one-year app subscription.
Business model
Zeph sells into healthcare providers and clinical teams, which deploy the platform with their own patients; the company states its virtual pulmonary rehabilitation program can be billed by provider entities through pulmonary rehabilitation codes as well as additional codes for longitudinal data collection. Hardware costs to the patient are absorbed: the Zeph Kit tablet and basic exercise equipment are supplied at no charge. A consumer-facing device bundle includes a one-year app subscription.
Provider reimbursement via pulmonary rehabilitation billing codes and codes for longitudinal data collection, plus a device bundle that includes a one-year subscription to the Zeph app.
Traction
Clinicians quoted on the company site, including Dr. Nader Mahmood and Dr. Anika Patel and an RN identified as April, describe improved patient enrollment, compliance and engagement. The site states Zeph is used by healthcare providers and reports outcomes across adherence and retention, quality of life, functional capacity, dyspnea and mental health, though no patient volumes or contract counts are disclosed.
▸Full profile — market position, technology, go-to-market, geography, history, risks & controversies
Market position
Zeph operates in virtual pulmonary rehabilitation and remote respiratory monitoring, a segment that also includes BreatheSuite, Conversio Health and FlexTogether according to a respiratory healthtech startup directory. The company frames its opportunity around large untreated demand, citing 24 million Americans living with COPD, 96% of COPD patients not receiving pulmonary rehabilitation, only 3% of eligible COPD patients completing traditional programs, and $50 billion in annual U.S. COPD costs.
The offering combines synchronous therapist-guided group rehabilitation delivered by video with asynchronous maintenance programming, real-time streamed pulse oximetry and heart rate for in-session safety supervision, supplied patient hardware, gamified exercises, billing support through pulmonary rehabilitation codes, and optional EHR integration — aimed at raising completion rates relative to facility-based rehabilitation.
Technology
A web app for clinicians and a pre-configured patient tablet run a telemedicine environment designed for group pulmonary rehabilitation visits, combined with AI-assisted personalization of care. Vitals are streamed in real time from FDA-approved Bluetooth-connected pulse oximetry and heart rate devices so clinicians can view live video and patient data simultaneously during sessions. The separate Zeph Trainer device uses clinical-grade respiratory sensors to measure lung function and breathing patterns, syncing wirelessly to iOS and Android apps that generate a breathability score and guided exercises. The platform can integrate with provider EHRs over roughly four weeks, ranging from PDF reports to structured assessment results and session progress; beyond the initial referral, Zeph states it does not pull data from the EHR.
Go-to-market
Zeph sells to clinical practices and healthcare organizations, positioning deployment as a three-step fit into existing workflows requiring only an internet-connected computer for the provider. Marketing emphasizes clinician testimonials, published evidence on pulmonary rehabilitation outcomes, billing enablement and low patient setup burden through shipped, preloaded tablets and 1:1 onboarding. A third-party respiratory healthtech startup directory also lists the company.
Healthcare providers, clinicians and care teams treating chronic respiratory disease, and their patients — including people with COPD from mild to severe, interstitial lung disease, pulmonary hypertension, bronchiectasis (cystic fibrosis and non-CF), severe asthma, post-COVID breathing problems, patients recovering from ICU stays or major respiratory events, lung volume reduction patients, lung cancer patients and lung transplant candidates and recipients.
Geography
United States.
History
Zeph Technologies was established in 2023 and is focused on AI-enabled pulmonary care, with a remote pulmonary rehabilitation platform for patients with chronic respiratory conditions, particularly COPD, as its primary product.
Risks & controversies
The program depends on patient internet connectivity and comfort with tablets among an older chronic-disease population, on provider reimbursement through pulmonary rehabilitation billing codes, and on IT-dependent EHR integration work at each customer site.
Compiled by commissioned research from 8 cited public sources — announcements, filings, and press listed under research sources below.
Key figures
latest reportedCompany-reported or press-reported figures, each dated to when it was claimed — not independently audited.
Related companies · 1
Companies working in the same space as Zeph.
▸Research sources · 8
primary sources listed
- Zephzephbreath.com · web
8 public sources were cited for this profile; the first-party ones are listed here.
Frequently asked questions
- What does Zeph do?
- Zeph is a virtual pulmonary rehabilitation platform that helps clinical teams deliver at-home care to COPD and other lung patients.
- Who founded Zeph?
- Zeph was founded by Shikha Anand, MD, MPH, Mimi Gendreau Kigawa, Francis Kigawa in 2023.
- Who are Zeph's investors?
- Zeph's investors include Antler, Techstars.
- Where is Zeph headquartered?
- Zeph is headquartered in New York City, US.


