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Tvardi Therapeutics

NASDAQ: TVRD

Houston, US · Founded 2017 · Delaware corporation · 20 employees on LinkedIn · 2 known investors

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Tvardi Therapeutics is a clinical-stage biopharmaceutical company developing oral small molecule STAT3 inhibitors to treat inflammatory and proliferative diseases. Its pipeline includes TTI-101, a direct STAT3 inhibitor in a Phase 2 trial for hepatocellular carcinoma, and TTI-109, a phosphate prodrug of TTI-101.

Founders & leadership

Tvardi Therapeutics was founded in 2017 by David J. Tweardy.

DJ
David J. TweardyFounder
JS
Josef SchoellExecutive
JW
Joseph W. StaufferExecutive
DCDerek Chalmers
Derek ChalmersExecutiveCo-founder, President & CEO, Board of Directors at Oban BioPharma
MEMichael E. Lewis
Michael E. LewisCo-founder Tvardi Therapeutics Inc.
FM
Frederique MenzaghiExecutive
IAImran Alibhai
Imran AlibhaiChief Executive OfficerImran Alibhai is Chief Executive Officer of Tvardi Therapeutics, a clinical-stage biopharmaceutical company developing STAT3 inhibitors for inflammatory and proliferative diseases. He has held executive, advisory, and investment roles across public and private life sciences companies.
RD
Ronald DePinhoNamed on SEC filing

Board

MV
Martin VogelbaumBoard director
JL
Jeffrey L. IvesBoard director
DS
Dean SlagelBoard director
HB
Harrison BainsBoard director

Investors · 2

Reported raises · per SEC filings

Form D private placements

$78.2M disclosed across 3 rounds · 2014–2021

▶$72.4MraisedJun 2021 · 32 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Jamie McNabDirector
  • Michael WyzgaDirector
  • Wallace HallDirector
  • Imran AlibhaiExecutive Officer, Director
  • Sujal ShahDirector
Offering amount
$75.1M
Amount sold
$72.4M
First sale
Jun 2021
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$5.6MraisedJul 2018 · 8 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • Ronald DePinhoDirector
  • David J. TweardyExecutive Officer, Director
Offering amount
$8.5M
Amount sold
$5.6M
First sale
Jun 2018
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$100KraisedDec 2014 · 1 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Josef SchoellExecutive Officer
  • Jeffrey L. IvesDirector
  • Joseph W. StaufferExecutive Officer
  • Derek ChalmersExecutive Officer, Director
  • Michael E. LewisExecutive Officer
  • Martin VogelbaumDirector
  • Dean SlagelDirector
  • Frederique MenzaghiExecutive Officer
  • Harrison BainsDirector
Offering amount
$100K
Amount sold
$100K
First sale
Dec 2014
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

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Frequently asked questions

What does Tvardi Therapeutics do?
Tvardi Therapeutics is a clinical-stage biopharmaceutical company developing oral small molecule STAT3 inhibitors to treat inflammatory and proliferative diseases. Its pipeline includes TTI-101, a direct STAT3 inhibitor in a Phase 2 trial for hepatocellular carcinoma, and TTI-109, a phosphate prodrug of TTI-101.
Who founded Tvardi Therapeutics?
Tvardi Therapeutics was founded by David J. Tweardy in 2017.
Who are Tvardi Therapeutics's investors?
Tvardi Therapeutics's investors include ShangBay Capital LLC, Solas BioVentures.
How much funding has Tvardi Therapeutics raised?
Tvardi Therapeutics has disclosed $78.2M raised across 3 rounds.
Where is Tvardi Therapeutics headquartered?
Tvardi Therapeutics is headquartered in Houston, US.