Tivic Health Systems
Fremont, US · Founded 2016 · Delaware corporation · 5 known investors
Valion Bio (Nasdaq: VBIO) is a clinical-stage immunotherapeutics company developing Entolimod, a TLR5 agonist that activates the innate immune system, for Acute Radiation Syndrome and oncology supportive care such as chemotherapy- and radiation-induced neutropenia. It also owns Velocity Bioworks, a U.S.-based contract development and manufacturing organization (CDMO) in San Antonio, Texas.
BiotechDefense TechHealthtech
Founders & leadership
Tivic Health Systems was founded in 2016 by Jennifer Ernst.
JE

Jennifer ErnstinFounder
MH
Michael HandleyExecutive
LW
Lisa WolfExecutive
JC
John ClaudeNamed on SEC filing
Board
CV
Christina ValauriBoard director
SB
Sheryle BoltonBoard director
DZ
Dean ZikriaBoard director
Investors · 5
Reported raises · per SEC filings
Form D private placements$36.2M disclosed across 3 rounds · 2019–2025
▶$16.3MraisedDec 2025 · 1 investors · BiotechnologyRule 506(b)
▶$16.3MraisedDec 2025 · 1 investors · Biotechnology
Rule 506(b)Officers, directors & promoters on the filing
- Michael HandleyExecutive Officer
- Lisa WolfExecutive Officer
- Jennifer ErnstExecutive Officer, Director, Promoter
- Sheryle BoltonDirector
- Dean ZikriaDirector
- Christina ValauriDirector
- Offering amount
- $16.3M
- Amount sold
- $16.3M
- First sale
- Dec 2025
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$12MraisedDec 2025 · 5 investors · BiotechnologyRule 506(b)
▶$12MraisedDec 2025 · 5 investors · Biotechnology
Rule 506(b)Officers, directors & promoters on the filing
- Jennifer ErnstExecutive Officer, Director, Promoter
- Christina ValauriDirector
- Michael HandleyExecutive Officer
- Sheryle BoltonDirector
- Lisa WolfExecutive Officer
- Dean ZikriaDirector
- Offering amount
- $75M
- Amount sold
- $12M
- First sale
- Dec 2025
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$7.9MraisedSep 2019 · 66 investors · BiotechnologyRule 506(b)
▶$7.9MraisedSep 2019 · 66 investors · Biotechnology
Rule 506(b)Officers, directors & promoters on the filing
- Sheryle BoltonDirector
- Dean ZikriaDirector
- John ClaudeDirector, Promoter
- Jennifer ErnstExecutive Officer, Director, Promoter
- Offering amount
- $10M
- Amount sold
- $7.9M
- Minimum investment
- $4K
- First sale
- Jul 2019
- Incorporated
- Corporation, California, 2016
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
In the news
Frequently asked questions
- What does Tivic Health Systems do?
- Valion Bio (Nasdaq: VBIO) is a clinical-stage immunotherapeutics company developing Entolimod, a TLR5 agonist that activates the innate immune system, for Acute Radiation Syndrome and oncology supportive care such as chemotherapy- and radiation-induced neutropenia. It also owns Velocity Bioworks, a U.S.-based contract development and manufacturing organization (CDMO) in San Antonio, Texas.
- Who founded Tivic Health Systems?
- Tivic Health Systems was founded by Jennifer Ernst in 2016.
- Who are Tivic Health Systems's investors?
- Tivic Health Systems's investors include Astia, Evolution VC Partners, Farvatn Venture, Mighty Capital, Portfolia.
- How much funding has Tivic Health Systems raised?
- Tivic Health Systems has disclosed $36.2M raised across 3 rounds.
- Where is Tivic Health Systems headquartered?
- Tivic Health Systems is headquartered in Fremont, US.

