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Spore

Entrepreneur First '23

Paris, FR · Founded 2023 · 71 employees on LinkedIn · 17 known investors

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Madison Lenormandunlockedknows Maxime Mistretta · together at Institut Pasteur (overlapped)
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×3knows the team · via Université Paris Cité
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knows the team · via University of Montpellier

Spore.Bio develops real-time microbial detection technology for industrial quality control, replacing traditional Petri dish culture methods used in factory settings. It combines photonics, AI, and biology to detect, quantify, and identify living microorganisms without reagents or culturing.

Also known as Spore Biotechnologies · Spore.Bio

Founders & leadership

Spore was founded in 2023 by Amine Raji, Maxime Mistretta, and Mohamed Tazi.

ARAmine Raji
Amine RajiinCo-Founder & CEOAmine Raji studied Physics at Lycée Janson-de-Sailly before earning a Master's in Industrial and Mechanical Engineering from ParisTech. He subsequently worked at Nestlé, where his focus was project engineering.
MMMaxime Mistretta
Maxime MistrettainCo-founder & CTOMaxime Mistretta earned a Master's in Biology from UTC and went on to complete both a PhD and postdoctoral research in microbiology at the Institut Pasteur. His background spans several years of bacterial science research in advanced laboratories.
MTMohamed Tazi
Mohamed TaziinCo-Founder & COOMohamed Tazi started out in the audit practice at Deloitte before turning to entrepreneurship. He launched his first company, the corporate fitness platform Gymlib, in 2013 and exited it in 2022.
MJMichael J. Miller
Michael J. MillerinVP of Scientific and Regulatory Affairs

Investors · 17

Also in the syndicate · 9

1st Kind Ventures1st Kind Ventures (Peugeot Family Office)EmergingTech VenturesFamille CFamille C (Clarins Family Office)Lord David PriorMehdi GhissassiPoint 72 VenturesRoxane Varza

Funding

SEC filings, press & company announcements

$23M disclosed across 1 of 4 rounds · 2021–2025

Source: company announcements and press reports — follow each round's link for the claim.

Company profile

researched Aug 2026

Spore.Bio is a Paris-based deeptech company founded in 2023 that builds instrumentation and machine learning software for rapid microbial detection in manufacturing environments. Its device projects light at specific wavelengths (described as UV-infrared) onto a sample and records the resulting spectral signature, which a pre-trained deep learning model analyses to determine whether bacteria or pathogens are present and at what concentration. The company markets the approach under the name TMSI (Transformer-based Multimodal Spectral Imaging) and describes it as a direct method able to detect, quantify and identify micro-organisms without culture, enrichment or dye.

The stated problem is the turnaround time of conventional microbiology: samples must generally be shipped to off-site specialised labs and incubated, which sources describe as taking roughly five days in agri-food and up to 14-20 days in pharmaceuticals and cosmetics. Spore.Bio positions its on-site testing as reducing this to minutes, with results surfaced through an internally developed dashboard so quality managers receive near real-time contamination signals and traceability data. Target application fields listed by the company include food, beverages, water and environment, cosmetics, pharmaceuticals and cell and gene therapies.

The founding team comprises CEO Amine Raji, a food and beverage manufacturing engineer who spent about six years in Nestlé factories and worked in more than 50 plants; CTO Maxime Mistretta, a PhD and postdoctoral microbiologist from the Pasteur Institute; and COO Mohamed Tazi, a second-time founder who previously sold Gymlib to EGYM. In January 2026 the company added Dr Michael J. Miller as VP of Scientific and Regulatory Affairs.

Founding story

Spore.Bio was founded in 2023 in Paris by Amine Raji, Maxime Mistretta and Mohamed Tazi. Raji, a food and beverage manufacturing engineer who worked for Nestlé and in more than 50 factories, observed how difficult it was to make consumer products safe given reliance on century-old testing techniques that constrained factory efficiency. He combined this industrial perspective with Mistretta's Pasteur Institute microbiology research background and Tazi's operating experience as a repeat founder to build a direct, real-time detection method.

Business model

Spore.Bio sells hardware testing systems together with software, deployed inside customer factories for in-house quality control, replacing the practice of sending samples to external laboratories. Sources describe signed commercial contracts and paid industrial deployments following proof-of-concept agreements, plus a waitlist for future deployments. Specific pricing or contract structures are not disclosed in the sources.

Sources indicate revenue from commercial contracts covering factory deployments of its devices, moving from paid proofs of concept in 2023 to industrial rollouts; no pricing, subscription or consumable pricing details are disclosed.

Traction

Sources report a first POC in March 2023, a first commercial contract in October 2023, a first validation study in December 2023, first prototypes shipped in May 2024, and commercial contracts covering up to 200 factories with a waitlist by February 2025. Headcount grew from 12 scientists and engineers at pre-seed to 30 in early 2025, with a stated target of 50 by end-2025; the company's team page lists 58 members and 8 open roles. The company states more than $35M raised and selection as a recipient of the Google.org AI for Science fund in January 2026.

Latest developments

Company posts dated January 2026 announce the appointment of Dr Michael J. Miller as VP of Scientific and Regulatory Affairs and selection as a recipient of Google.org's $20 million AI for Science fund, which the company says made it the only startup chosen worldwide. Its timeline lists a March 2026 launch of TMSI, described as a reagent-free, culture-free microbiology platform delivering results in under 10 minutes. The team page reports 58 employees, more than $35M raised and 8 open roles.

Full profile — market position, technology, go-to-market, geography, history, risks & controversies

Market position

Spore.Bio positions itself as offering the first direct, culture-free method for industrial microbial testing, contrasting with petri-dish culture and interim approaches such as ATP testing and solid-phase cytometry. It acquired Greentropism, described as a competitor in spectral analysis and spectroscopy-based quality control. Investors describe it as applying photonics and AI to reach detection levels comparable to traditional methods in real time.

Differentiation claimed in the sources rests on eliminating culture, enrichment and dyes, enabling on-site testing on the factory floor rather than off-site lab shipment, and compressing multi-day turnaround into minutes (under 10 minutes for the TMSI platform). Additional stated moats are the proprietary deep learning model, access to the Pasteur Institute biobank for training data, and IP acquired with Greentropism.

Technology

The platform combines optics/photonics with deep learning. Light at specific wavelengths (UV-infrared) is projected at a sample and its spectral signature is recorded, then classified by a deep learning model trained on contaminated and uncontaminated data. The company brands this as TMSI, Transformer-based Multimodal Spectral Imaging, and describes it as reagent-free and culture-free, capable of detecting, quantifying and identifying living microorganisms in under 10 minutes. The trained model is described as the company's principal asset; a partnership with the Pasteur Institute provides access to its bacteria biobank, and the acquisition of Greentropism added expertise and IP in spectral analysis, chemometrics and spectroscopy-based quality control.

Go-to-market

The company began with proofs of concept with industrial partners in 2023, converted to paid contracts, and shipped its first prototypes into factories in May 2024, iterating with hands-on industrial feedback before broader commercialisation. It reports signed contracts covering up to 200 factories and an oversubscribed waitlist for prototypes, and stated plans to deploy dozens of systems and prepare for commercialisation before the end of 2025. Academic credibility is supported by the Pasteur Institute partnership.

Manufacturers subject to microbiological quality control, initially food and beverage producers, and extending to cosmetics companies (which face pressure to remove preservatives), pharmaceutical manufacturers, and producers of advanced therapies such as gene and cell therapies whose products can have shelf lives as short as seven days. Water and environmental testing is also listed as an application field.

Geography

Headquartered in Paris, France, with a team described as spanning 18 nationalities. Investor materials referenced plans to deploy hardware and software systems globally, and the CEO's background covers factories worldwide, but specific country deployments are not detailed in the sources.

History

Founded in 2023, the company signed its first proof of concept in March 2023 and, per its own timeline, completed a pre-seed round in May 2023 followed by an €8 million round closed in September 2023; press coverage dates the €8 million (about $8.3 million) pre-seed led by LocalGlobe to December 2023, with public announcement of the company's emergence from stealth in February 2024. A first commercial contract came in October 2023 and a first validation study in December 2023. First prototypes shipped to factories in May 2024. A $23 million (€22 million) Series A led by Singular was announced in February 2025, alongside the acquisition of Greentropism and a partnership with the Pasteur Institute. In January 2026 the company was named a recipient of the Google.org AI for Science fund and hired Dr Michael J. Miller as VP of Scientific and Regulatory Affairs, with a TMSI platform launch dated March 2026 on its timeline.

Risks & controversies

Sources contain inconsistent funding data: the pre-seed is variously dated May 2023, September 2023 and December 2023 and sized at €8 million, €7.9 million or $9 million, and total funding is reported as €29.9 million, $32.0 million or more than $35 million; one aggregator also lists Series A investors (Project A Ventures, Christian Reber, Nicolas Brusson, Iris Capital, Partech, Entrepreneur First) not corroborated by primary press coverage. Third-party commentary notes that regulatory acceptance of non-culture rapid methods and demonstrated false-positive/negative performance in real deployments remain determinants of commercial success. Headcount figures for early 2025 differ between sources (25 vs 30). No litigation or controversy is reported in the sources.

Compiled by commissioned research from 8 cited public sources — announcements, filings, and press listed under research sources below.

Key figures

latest reported
Average team ageJan 202631 years
Factories covered by signed commercial contractsFeb 2025200 factories
Gender parityJan 202655%
HeadcountJan 202658 employees
Headcount targetDec 202550 employees
Nationalities represented in teamJan 202618
Open positionsJan 20268
Team size at pre-seedFeb 202412 scientists and engineers
Total funding raisedFeb 2025$29.9M
Total funding raised (company-stated)Jan 2026$35M+

Company-reported or press-reported figures, each dated to when it was claimed — not independently audited.

Timeline · 11

launches, deals, and filings
Mar 2026
Launch of TMSI platform

Company timeline states Spore.Bio launches TMSI (Transformer-based Multimodal Spectral Imaging), described as a reagent-free, culture-free microbiology platform that detects, quantifies and identifies living microorganisms in under 10 minutes.

source ↗

Jan 2026
Dr Michael J. Miller joins as VP of Scientific and Regulatory Affairs

Miller, described as an expert in rapid microbiological methods and contamination control with nearly 40 years of experience in pharmaceutical microbiology and validation of rapid microbiological methods, joins the company.

source ↗

Jan 2026
Selected for Google.org AI for Science fund

Spore.Bio named a recipient of the Google.org $20 million AI for Science fund; the company states it was the only startup selected worldwide by the fund.

source ↗

Feb 2025
$23M Series A led by Singular

Oversubscribed Series A (reported as $23 million / €22 million) led by Singular with Point72 Ventures, 1st Kind Ventures, Station F, Lord David Prior and returning investors LocalGlobe, No Label Ventures and Famille C.

$23M source ↗

Feb 2025
Acquisition of Greentropism

Spore.Bio acquired Greentropism, a competitor specialising in spectral analysis, chemometrics and spectroscopy-based quality control with AI-assisted modeling, for its technical expertise and IP. Greentropism had previously raised €3 million.

source ↗

Feb 2025
Academic partnership with Institut Pasteur

Partnership giving Spore.Bio access to the Pasteur Institute's bacteria biobank to train and broaden its detection models.

source ↗

May 2024
First prototype shipped to factories

First devices deployed from the lab into customer factories.

source ↗

Feb 2024
Spore.Bio emerges from stealth with €8M pre-seed led by LocalGlobe

LocalGlobe (Phoenix Court) announced Spore.Bio's exit from stealth and an €8 million pre-seed round to develop and deploy its AI-powered pathogen detection device and grow the team; other sources date the round to December 2023.

$8.3M source ↗

Dec 2023
First full-scale validation study

Company reports its first validation study confirmed the performance of its AI model, preceding the first prototype generation.

source ↗

Oct 2023
First commercial contract

Transition from proof-of-concept to paid industrial deployment.

source ↗

Mar 2023
First proof-of-concept signed with industrial partner

Company timeline reports its first POC agreement with industrial partners weeks after launch.

source ↗

Dated company events from announcements, filings, and press; legal rows summarize public dockets and regulator releases.

In the news

Research sources · 8

primary sources listed

8 public sources were cited for this profile; the first-party ones are listed here.

Frequently asked questions

What does Spore do?
Paris-based deeptech developing AI and photonics-based microbiology testing that detects microbes without culture.
Who founded Spore?
Spore was founded by Amine Raji, Maxime Mistretta, Mohamed Tazi in 2023.
Who are Spore's investors?
Spore's investors include Entrepreneur First, Kima Ventures, Point72 Ventures, Teampact.ventures, LocalGlobe, NO LABEL VENTURES, Singular, STATION F.
How much funding has Spore raised?
Spore has disclosed $23M raised across 1 of its 4 known rounds.
Where is Spore headquartered?
Spore is headquartered in Paris, FR.