Sisu Pharma
Chapel Hill, US · Founded 2019 · Delaware corporation
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Sisu Pharma develops therapeutics targeting Heat Shock Factor 1 (HSF1), using its HI-LiTe platform to create selective HSF1 degraders for oncology and HSF1 activators for neurodegenerative diseases. Its compounds are aimed at therapy-resistant cancers and other difficult-to-treat diseases.
Founders & leadership
Sisu Pharma was founded in 2019 by Sean E. O'Brien.
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Sean E. O'BrienFounder, Chief Executive OfficerSean O'Brien holds a PhD in Computational Chemistry and has over 20 years of experience in drug discovery, clinical development, and biotech entrepreneurship, including roles at Pfizer and Accelrys; he is founder and CEO of Sisu Pharma, which he co-founded alongside G4 Oncology and Trilogy Therapeutics.
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Jiaoti HuangNamed on SEC filing
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Sean O'BrienCo-founder and CEO
Board
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Michael Serrano-WuBoard director
Reported raises · per SEC filings
Form D private placements$1.7M disclosed across 1 round · 2020
▶$1.7MraisedJul 2020 · 1 investors · PharmaceuticalsRule 506(b)
▶$1.7MraisedJul 2020 · 1 investors · Pharmaceuticals
Rule 506(b)Officers, directors & promoters on the filing
- Jiaoti HuangExecutive Officer, Director, Promoter
- Dennis ThieleExecutive Officer, Director, Promoter
- Michael Serrano-WuDirector
- Sean O'BrienExecutive Officer, Director, Promoter
- Offering amount
- $4M
- Amount sold
- $1.7M
- First sale
- Jun 2020
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
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Companies working in the same space as Sisu Pharma.
Frequently asked questions
- What does Sisu Pharma do?
- Sisu Pharma develops therapeutics targeting Heat Shock Factor 1 (HSF1), using its HI-LiTe platform to create selective HSF1 degraders for oncology and HSF1 activators for neurodegenerative diseases. Its compounds are aimed at therapy-resistant cancers and other difficult-to-treat diseases.
- Who founded Sisu Pharma?
- Sisu Pharma was founded by Sean E. O'Brien in 2019.
- How much funding has Sisu Pharma raised?
- Sisu Pharma has disclosed $1.7M raised across 1 round.
- Where is Sisu Pharma headquartered?
- Sisu Pharma is headquartered in Chapel Hill, US.

