OpenBench
San Francisco, US · Founded 2019 · Delaware corporation
OpenBench runs AI-enabled structure-based virtual screening to identify small molecule hit series for biotech drug discovery programs, screening large compound libraries and charging only for hits that meet a client-defined profile. It works with clients' own assays and CROs, offering a success-driven model where collaborators purchase resulting IP outright.
Founders & leadership
OpenBench was founded in 2019 by James Thompson and James Yoder.
JT
James ThompsonCo-founder
JY

James YoderCo-founder
Reported raises · per SEC filings
Form D private placements$2.7M disclosed across 3 rounds · 2020–2021
▶$2.3MraisedApr 2022 · 16 investors · Other TechnologyRule 506(b)
▶$2.3MraisedApr 2022 · 16 investors · Other Technology
Rule 506(b)Officers, directors & promoters on the filing
- James ThompsonExecutive Officer, Director, Promoter
- James YoderExecutive Officer, Director, Promoter
- Offering amount
- $2.5M
- Amount sold
- $2.3M
- First sale
- Dec 2021
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06b
▶$150KraisedApr 2021 · 6 investors · OtherRule 506(b)
▶$150KraisedApr 2021 · 6 investors · Other
Rule 506(b)Officers, directors & promoters on the filing
- James ThompsonExecutive Officer, Director, Promoter
- James YoderExecutive Officer, Director, Promoter
- Offering amount
- $150K
- Amount sold
- $150K
- First sale
- Mar 2021
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06b
▶$300KraisedJan 2020 · 6 investors · OtherRule 506(b)
▶$300KraisedJan 2020 · 6 investors · Other
Rule 506(b)Officers, directors & promoters on the filing
- James ThompsonExecutive Officer, Director
- James YoderExecutive Officer, Director
- Offering amount
- $300K
- Amount sold
- $300K
- First sale
- Jan 2020
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Competitors · 4
by search overlapHugging Face8 shared keywordsHugging Face is a collaboration platform that hosts and provides access to machine learning models, datasets, and applications. It offers both open-source tools for the ML community and paid compute and enterprise solutions for teams building AI applications.
Bench6 shared keywordsBench builds engineering software for hardware development in the AI era. The company is founded by a team of engineers focused on tools for hardware engineering.
Work Bench5 shared keywordsWork-Bench is a New York City seed-stage venture capital fund that invests in early-stage founders building enterprise, SaaS, and infrastructure software, with a focus on go-to-market support. It backs companies across AI/ML, cybersecurity, dev tools, and enterprise applications.
Benchsci4 shared keywordsBenchSci builds AI infrastructure for preclinical drug discovery, using machine learning that reads scientific literature to extract experimental evidence and map disease biology for biopharma R&D teams. Its tools help scientists select reagents and model systems and reason about targets, pathways, and mechanisms to reduce failed experiments.
Companies competing with OpenBench for the same Google search keywords, organic and paid, via search-intersection analysis.
Frequently asked questions
- What does OpenBench do?
- OpenBench runs AI-enabled structure-based virtual screening to identify small molecule hit series for biotech drug discovery programs, screening large compound libraries and charging only for hits that meet a client-defined profile. It works with clients' own assays and CROs, offering a success-driven model where collaborators purchase resulting IP outright.
- Who founded OpenBench?
- OpenBench was founded by James Thompson, James Yoder in 2019.
- How much funding has OpenBench raised?
- OpenBench has disclosed $2.7M raised across 3 rounds.
- Where is OpenBench headquartered?
- OpenBench is headquartered in San Francisco, US.



