Open Protein
2 known investors
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OpenProtein.AI offers protein language models and AI infrastructure for protein engineering, covering de novo sequence design, variant effect prediction, in silico screening, and training specialized models on proprietary data. Accessible via a no-code GUI and APIs, it serves biology and computational research teams working in protein design and drug discovery.
Founders & leadership
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Tristan BeplerTristan Bepler holds a PhD from MIT, where he studied machine learning methods for protein sequence, structure, and function under Bonnie Berger. He is the founder of Open Protein, which develops AI infrastructure and language models for protein engineering and drug discovery.
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Timothy F. Truong Jr
Investors · 2
The E14 Fundlisted by The E14 FundCambridge · $1M – $5M
How we know: The E14 Fund's portfolio page · the VCSheet dataset · Not right? Tell us
Frequently asked questions
- What does Open Protein do?
- OpenProtein.AI offers protein language models and AI infrastructure for protein engineering, covering de novo sequence design, variant effect prediction, in silico screening, and training specialized models on proprietary data. Accessible via a no-code GUI and APIs, it serves biology and computational research teams working in protein design and drug discovery.
- Who founded Open Protein?
- Open Protein was founded by Tristan Bepler.
- Who are Open Protein's investors?
- Open Protein's investors include NSG Ventures, The E14 Fund.

