NK-One Therapeutics
Wayne, US · Founded 2026 · Delaware corporation
NK-One Therapeutics is a biotechnology company developing a first-in-class intrathecal molecular therapy (SP-SAP) that selectively disables NK-1 receptor pain-signaling neurons in the spine to treat refractory pain in end-stage cancer patients. The therapy is in a Phase 1 clinical trial and is also intended for veterinary use.
Founders & leadership
MP
Marco PappagalloSecretary
MS
Michael ShineChief Executive Officer and President
M
MikeCEO
DP
Dr. PappagalloChief Medical Officer / Medical Advisor
P
PaulDrug Development Lead
Reported raises · per SEC filings
Form D private placements$290K disclosed across 1 round · 2026
▶$290KraisedApr 2026 · 7 investors · BiotechnologyRule 506(b)
▶$290KraisedApr 2026 · 7 investors · Biotechnology
Rule 506(b)Officers, directors & promoters on the filing
- Marco PappagalloExecutive Officer, Director
- Michael ShineExecutive Officer, Director
- Offering amount
- $310K
- Amount sold
- $290K
- First sale
- Mar 2026
- Incorporated
- Corporation, Delaware, 2026
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Competitors · 3
by search overlapNKore Biotherapeutics9 shared keywordsNKore BioTherapeutics is a cellular-based biotherapeutics company developing an allogeneic immunotherapy platform based on a proprietary method of activating natural killer (NK) cells, called Supercharged NK (sNK) cells. Its lead therapy, NK101, targets solid and blood cancers in adult and pediatric patients, with human clinical trials planned in the United States beginning in 2027.
Bioworld8 shared keywordsBioWorld is a suite of daily news and data services covering therapeutics, medical technology, biopharma business transactions, and drug R&D, serving biopharmaceutical and medtech industry professionals. Owned by Clarivate, it publishes products including BioWorld, BioWorld Science, and BioWorld Asia with reporting from writers stationed globally.
Nkarta, Inc.8 shared keywordsNkarta is a biotech company developing allogeneic CAR NK cell therapies for autoimmune diseases, aiming to offer safer and more accessible alternatives to autologous CAR-T treatments. Its lead program, NKX019, targets the CD19 antigen for B cell-mediated autoimmune conditions such as lupus nephritis and systemic sclerosis.
Companies competing with NK-One Therapeutics for the same Google search keywords, organic and paid, via search-intersection analysis.
Frequently asked questions
- What does NK-One Therapeutics do?
- NK-One Therapeutics is a biotechnology company developing a first-in-class intrathecal molecular therapy (SP-SAP) that selectively disables NK-1 receptor pain-signaling neurons in the spine to treat refractory pain in end-stage cancer patients. The therapy is in a Phase 1 clinical trial and is also intended for veterinary use.
- How much funding has NK-One Therapeutics raised?
- NK-One Therapeutics has disclosed $290K raised across 1 round.
- Where is NK-One Therapeutics headquartered?
- NK-One Therapeutics is headquartered in Wayne, US.
