/Companies

NK-One Therapeutics

Wayne, US · Founded 2026 · Delaware corporation

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NK-One Therapeutics is a biotechnology company developing a first-in-class intrathecal molecular therapy (SP-SAP) that selectively disables NK-1 receptor pain-signaling neurons in the spine to treat refractory pain in end-stage cancer patients. The therapy is in a Phase 1 clinical trial and is also intended for veterinary use.

Founders & leadership

MP
Marco PappagalloSecretary
MS
Michael ShineChief Executive Officer and President
M
MikeCEO
DP
Dr. PappagalloChief Medical Officer / Medical Advisor
P
PaulDrug Development Lead

Reported raises · per SEC filings

Form D private placements

$290K disclosed across 1 round · 2026

▶$290KraisedApr 2026 · 7 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Marco PappagalloExecutive Officer, Director
  • Michael ShineExecutive Officer, Director
Offering amount
$310K
Amount sold
$290K
First sale
Mar 2026
Incorporated
Corporation, Delaware, 2026
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

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Frequently asked questions

What does NK-One Therapeutics do?
NK-One Therapeutics is a biotechnology company developing a first-in-class intrathecal molecular therapy (SP-SAP) that selectively disables NK-1 receptor pain-signaling neurons in the spine to treat refractory pain in end-stage cancer patients. The therapy is in a Phase 1 clinical trial and is also intended for veterinary use.
How much funding has NK-One Therapeutics raised?
NK-One Therapeutics has disclosed $290K raised across 1 round.
Where is NK-One Therapeutics headquartered?
NK-One Therapeutics is headquartered in Wayne, US.