InflammX Therapeutics
Tampa, US · Founded 2020 · Delaware corporation
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InflammX Therapeutics develops Xiflam, a once-daily oral small molecule that inhibits the pathologically open Connexin43 hemichannel to modulate the NLRP3 inflammasome, targeting inflammation in retinal disease. Its lead indication is the dry form of age-related macular degeneration (dry AMD), for which there is currently no approved pharmacologic treatment.
Founders & leadership

Reported raises · per SEC filings
Form D private placements$15.4M disclosed across 2 of 3 rounds · 2020–2022
▶Undisclosed amountofferedMay 2022 · 2 investors · BiotechnologyRule 506(b)
- Jason WernerDirector
- Phil RosenfeldDirector
- David BoyerDirector
- Rajiv ShuklaDirector
- Richard RubinoDirector
- James BlairDirector
- David PoolExecutive Officer
- Brian LevyExecutive Officer, Director
- First sale
- May 2022
- Incorporated
- Corporation, Delaware, 2020
- Federal exemptions
- 06b
▶$8.4MraisedNov 2021 · 6 investors · BiotechnologyRule 506(b)
- James BlairDirector
- Brian LevyExecutive Officer, Director
- David BoyerDirector
- David PoolExecutive Officer
- Jason WernerDirector
- Rajiv ShuklaDirector
- Phil RosenfeldDirector
- Offering amount
- $8.4M
- Amount sold
- $8.4M
- First sale
- Nov 2021
- Incorporated
- Corporation, Delaware, 2020
- Federal exemptions
- 06b
▶$7MraisedJan 2021 · 4 investors · BiotechnologyRule 506(b)
- Brian LevyExecutive Officer, Director
- David PoolExecutive Officer
- Rajiv ShuklaDirector
- Phil RosenfeldDirector
- David BoyerDirector
- James BlairDirector
- Offering amount
- $7M
- Amount sold
- $7M
- First sale
- Dec 2020
- Incorporated
- Corporation, Delaware, 2020
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
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Frequently asked questions
- What does InflammX Therapeutics do?
- InflammX Therapeutics develops Xiflam, a once-daily oral small molecule that inhibits the pathologically open Connexin43 hemichannel to modulate the NLRP3 inflammasome, targeting inflammation in retinal disease. Its lead indication is the dry form of age-related macular degeneration (dry AMD), for which there is currently no approved pharmacologic treatment.
- How much funding has InflammX Therapeutics raised?
- InflammX Therapeutics has disclosed $15.4M raised across 2 of its 3 known rounds.
- Where is InflammX Therapeutics headquartered?
- InflammX Therapeutics is headquartered in Tampa, US.
