Ilab
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South Korean drug developer working on small-molecule therapies for cancer, inflammation and immune disorders.
Also known as iLab Co., Ltd
Investors · 1
Company profile
researched Aug 2026iLab Co., Ltd is a South Korea-based pharmaceutical company, listed with a 2017 establishment year and a location in Gyeonggi-do, that develops small-molecule drug candidates. Its disclosed pipeline spans oncology, inflammatory and immune-system indications, with programs directed at targets including TNF-alpha, PD-L1, CSF-1R, IL-6 and a CSF-2R x PD-L1 combination.
The company is classified as a holding company and is recorded as both originator and active organization for its candidates, indicating in-house origination of its programs. Its most advanced asset, IA-14069, an oral TNF-alpha inhibitor for rheumatoid arthritis, has reached Phase 1. Other assets are at preclinical (IA-05592, a PD-L1 inhibitor for neoplasms) or discovery stage (CSF-1R and CSF-2R x PD-L1 oncology projects, and an IL-6-directed anti-inflammatory project).
Traction
Two Phase 1 studies of IA-14069 are recorded with iLab as sponsor: a first-in-human, double-blind, placebo-controlled single ascending dose study in healthy male subjects (NCT05317741, started 23 Aug 2021, completed), and a randomized, double-blind, placebo-controlled multiple ascending dose study in healthy subjects and rheumatoid arthritis patients including a methotrexate drug-drug interaction extension and preliminary efficacy assessment (NCT05533372, started 10 Oct 2022, recruiting). The pipeline comprises one Phase 1, one preclinical and three discovery-stage programs.
Latest developments
In November 2025, the British Journal of Pharmacology published a study on IA-0130, an oxindole-derivative gp130 binder, reporting inhibition of IL-6/gp130/STAT3 signalling and anticancer activity in ovarian cancer models, including anticancer drug-resistant lines.
▸Full profile — market position, technology, go-to-market, geography, history
Market position
Clinical-stage small-molecule developer whose lead program has completed a first-in-human study and entered multiple ascending dose testing, with remaining assets at preclinical and discovery stages.
Technology
iLab focuses on small-molecule drug discovery. Programs target TNF-alpha (TNF-alpha inhibition), PD-L1 (PD-L1 inhibition), CSF-1R, IL-6 and a dual CSF-2R x PD-L1 mechanism (CSF-2R antagonism). Related published research describes IA-0130, a 3-(1,3-diarylallylidene)oxindole derivative selected from 24 synthesised analogues for its binding to gp130, which inhibited gp130/STAT3 phosphorylation and suppressed growth, migration, invasion and metastasis in ovarian cancer and drug-resistant ovarian cancer cell lines, and delayed tumour growth after oral administration in a human ovarian cancer mouse xenograft model.
Go-to-market
Patients with rheumatoid arthritis, ovarian and other neoplasms, and inflammatory and immune-system diseases, addressed through pharmaceutical development.
Geography
Headquartered in Gyeonggi-do, South Korea.
History
Company records list 2017 as the founding year. First-in-human dosing of lead candidate IA-14069 began in August 2021, followed by a multiple ascending dose Phase 1 study starting in October 2022.
Compiled by commissioned research from 7 cited public sources — announcements, filings, and press listed under research sources below.
Key figures
latest reportedCompany-reported or press-reported figures, each dated to when it was claimed — not independently audited.
Timeline · 3
launches, deals, and filingsBritish Journal of Pharmacology article reporting that IA-0130, a 3-(1,3-diarylallylidene)oxindole derivative, binds gp130, inhibits IL-6/gp130/STAT3 signalling and suppresses ovarian cancer growth and metastasis in vitro and in a mouse xenograft model.
Randomized, double-blind, placebo-controlled multiple ascending dose study in healthy subjects and in rheumatoid arthritis patients on stable methotrexate, including a drug-drug interaction extension and preliminary efficacy assessment; listed as recruiting.
Double-blind, placebo-controlled single ascending dose study evaluating safety, tolerability, pharmacokinetics, food effect and pharmacodynamics of a single oral dose of IA-14069 in healthy male subjects; listed as completed.
Dated company events from announcements, filings, and press; legal rows summarize public dockets and regulator releases.
▸Research sources · 7
primary sources listed
- ilabcorp.co.krilabcorp.co.kr · web
7 public sources were cited for this profile; the first-party ones are listed here.
Frequently asked questions
- What does Ilab do?
- South Korean drug developer working on small-molecule therapies for cancer, inflammation and immune disorders.
- Who are Ilab's investors?
- Ilab's investors include Atinum Investment Co. Ltd..
