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Empirical Bio

Entrepreneur First '24

London, GB · Founded 2024 · 2 known investors

Find your way into Empirical Bio

422 people in our graph share verified history with the Empirical Bio team — schools, employers, funds. One of them is your warm intro.

Tobi Cokerunlockedknows Jamie Weigold · together at Stealth (overlapped)
×2knows the team · via University of Cambridge
×5knows the team · via Entrepreneur First
×2knows the team · via UCL
×2knows the team · via Stealth

Empirical Bio builds machine learning software that predicts and optimizes the structure of enzymes and other biomolecules. Biotech research teams use it to narrow down candidates computationally before moving to the bench, which reduces the number of laboratory testing cycles required.

Also known as Empirical

Founders & leadership

Empirical Bio was founded in 2024 by Jamie Weigold.

JWJamie Weigold
Jamie WeigoldinCEOJamie Weigold finished among the top three computer science students in his cohort at the University of Cambridge and went on to work at a prominent BioML lab. He also built an image foundation model that outperformed Stable Diffusion, developed over six weeks.

Investors · 2

Company profile

researched Aug 2026

Empirical Bio is a London-based company founded in 2024 that develops machine learning software for predicting and optimizing the structures of enzymes and other biomolecules, with the aim of letting biotech research teams shortlist candidates computationally and reduce the number of laboratory testing cycles required. The company appears in the Entrepreneurs First portfolio directory, which indexes companies by location, industry, founding year and funding stage.

As of the material reviewed, the company's public web presence is minimal: its website at empirical.sh consists of a placeholder page marked "Launching Soon" with an email sign-up form for updates, carrying a 2024 copyright notice. No product documentation, customer references, pricing, team page or funding disclosures are available on the public site.

Note on name twins: several sources retrieved under similar names refer to Empirical Bioscience, Inc., a US developer and manufacturer of enzymes, proteins and reagents acquired by Fortis Life Sciences. That is a distinct company and its facts are not included in this profile.

Traction

No traction metrics, customers, partnerships or funding amounts are disclosed in the available sources.

Latest developments

The company's website was, at the time of retrieval, a pre-launch placeholder stating "Launching Soon" and collecting email addresses for future updates, indicating the product had not yet been publicly released.

Full profile — geography

Geography

The company is associated with London, United Kingdom; the Entrepreneurs First portfolio directory from which the company is listed segments companies across locations including London.

Compiled by commissioned research from 5 cited public sources — announcements, filings, and press listed under research sources below.

Companies House · registry record

View on Companies House ↗
Registered name
EMPIRICAL BIO LTD
Company number
16181256
Status
Active
Company type
Private limited company
Incorporated
13 Jan 2025
Registered office
86-90 Paul Street, London, EC2A 4NE
Nature of business (SIC)
58290 — Other software publishing62012 — Business and domestic software development
Accounts
last made up to 31 Dec 2025 · next due 30 Sept 2027
Confirmation statement
last made up to 12 Jan 2026 · next due 26 Jan 2027

Current officers · 1

  • Jamie Weigold director, appointed 13 Jan 2025

Source: Companies House public register · retrieved 30 Aug 2026. Contains public sector information licensed under the Open Government Licence v3.0.

Research sources · 5

primary sources listed

5 public sources were cited for this profile; the first-party ones are listed here.

Frequently asked questions

What does Empirical Bio do?
London-based Entrepreneurs First-backed startup building ML software to predict and optimize enzyme and biomolecule structures.
Who founded Empirical Bio?
Empirical Bio was founded by Jamie Weigold in 2024.
Who are Empirical Bio's investors?
Empirical Bio's investors include Entrepreneur First, Transpose Platform Management.
Where is Empirical Bio headquartered?
Empirical Bio is headquartered in London, GB.