Clean OS
Techstars '24Milan, IT · Founded 2024 · 8 employees on LinkedIn · 1 known investors
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CleanOS makes personalized electric toothbrushes with custom brush heads designed from individual intraoral scans. The device targets consumers seeking faster, more effective daily oral hygiene through automated cleaning adapted to each person's mouth shape.
Also known as Clean OS holding S.r.l. · Clean OS S.r.l. · CleanOS
Investors · 1
How we know: the Techstars portfolio · open dataset · Top 3000 Accelerator Startups (no YC) 2026-08 · Not right? Tell us
Company profile
researched Sep 2026Clean OS (CleanOS) is an Italian oral-care company that develops the CleanOS Smartbrush, a full-arch electric toothbrush whose brush heads are manufactured from an intraoral scan of the individual user's mouth. Rather than being moved across the teeth by the user, the device is inserted into the mouth and activated with a single button, cleaning one dental arch in about 30 seconds. The company positions the product against conventional electric toothbrushes on the grounds that standard heads are identical for every mouth while real arches differ in gum heights, interdental spacing, tooth shape and arch geometry.
The product line comprises the Smartbrush (EUR 200) and a CloudFoam micro-foam toothpaste (EUR 20) formulated to spread into narrow interdental spaces and to suit the arch-shaped device. The Smartbrush is described as using soft bristles, antibacterial and biocompatible CE-certified water-resistant materials, an ergonomic form, pressure sensors for controlled brushing force, and a wireless dock charge lasting up to two weeks. Custom heads are stated to last six to nine months versus three months for conventional brushes. The company publishes contraindications: the device is not indicated for users under 18 or for adults with conditions including severe dental crowding, full removable or full-arch implant prostheses, fixed traditional orthodontic therapy, severe periodontal tooth mobility, pronounced gag reflex, limited mouth opening, craniofacial malformations, certain neurological, neuromuscular, temporomandibular or psychiatric conditions, and oral autoimmune disease.
Beyond the device, the company describes a broader oral-care offering built around a network of affiliated Italian dental clinics providing discounted treatments, complementary products such as mouthwashes, whitening treatments and oral-microbiota supplements, and a digital clinical record allowing users to follow their oral health status.
Founding story
Clean OS was founded in 2024 by Giovanni Tuccari (CEO, a former BCG consultant with experience building international startups and scaleups), Pietro Pastore (Chief Medical Officer, a specialist dentist previously involved in the growth of invisible-aligner company Impress in Italy) and Francesco Anzalone (CTO, an electronic engineer with hardware design and product development experience). The company states it was created to address the observation that roughly 80% of people suffer from easily preventable oral pathologies, attributing this not to a lack of brushing but to the scope for human error in current brushing methods.
Business model
Clean OS sells hardware and consumables direct to consumers through its own online store, with the Smartbrush listed at EUR 200 and the CloudFoam toothpaste at EUR 20. The initial kit includes the Smartbrush, two custom brush heads for the upper and lower arch, a magnetic charger, bathroom accessories and a travel case, three months of CleanOS toothpaste, and a free intraoral scan at a partner clinic. Brush heads last six to nine months and are reordered on a reminder-confirmation basis without a repeat scan, creating recurring consumable sales. The crowdfunding material also describes planned adjacent revenue lines: complementary oral-care products such as mouthwashes, whitening treatments and oral-microbiota supplements, discounted access to dental treatments through the affiliated clinic network, and a digital clinical record for tracking oral health.
Revenue comes from one-off device sales plus recurring sales of personalised replacement brush heads and consumables such as the CloudFoam toothpaste, with planned additional lines in complementary oral-care products and mediated access to dental treatments via affiliated clinics. Company projections presented to crowdfunding investors indicated roughly EUR 800,000 of potential revenue in 2025 and a target of EUR 45 million in revenue with a 21% EBITDA margin by the end of 2028. A third-party business-data profile lists an estimated annual revenue of about $770,000 and a company size of 1-10 employees; those figures are modelled estimates rather than reported results.
Traction
The equity crowdfunding campaign closed overfunded at EUR 597,588 from 144 investors, 398% of its EUR 150,000 target, against a EUR 600,000 maximum. The company reported partnerships with more than 40 Italian dental practices, an affiliated network of 43 clinics, a significant waiting list ahead of launch, and backing from BlueThink SpA and Techstars. Its website sells the Smartbrush and CloudFoam toothpaste directly and cites early-user survey figures of 100% feeling a cleaner mouth from first use, 92% perceiving greater gentleness on the gums, 100% reporting simpler and faster oral hygiene and 94% saying they would not return to their previous routine; the sample size for these figures is not stated.
▸Full profile — market position, technology, go-to-market, geography, history
Market position
The company operates in the electric toothbrush and oral-care device market, citing a global toothbrush market projected at $16.5 billion by 2028 with a 1.9% CAGR and an electric toothbrush segment growing at a 6.3% CAGR to $5.7 billion, driven by electrification and premiumisation. It names Y-Brush, Feno and Samba Robotics as competitors among devices that simplify the brushing routine, and cites Burst Oral Care, Quip and Foreo as emerging brands that scaled past EUR 100 million in revenue. Clean OS positions itself as an early-stage entrant differentiated by per-user personalisation and a modular, patent-pending design.
The company's stated differentiator is that the Smartbrush is the only device whose heads are produced from an intraoral scan of the user's own mouth, combined with an arch-shaped, modular architecture that it says allows fully personalised devices to be manufactured at industrial scale from a digital scan or dental impression. That technology is described as patent-pending and as developed after analysis of more than 500 patents, and the company claims clinically tested proprietary technology, plaque removal above 95% against a cited 65% average, single-button operation that removes user technique error, and cleaning time of 30 seconds per arch against at least two minutes for a conventional brush.
Technology
The core technology is an arch-shaped, modular brush head architecture that allows a fully personalised head to be produced from an intraoral digital scan or dental impression, which the company says enables mass personalisation at industrial scale; the technology is described as patent-pending. The Smartbrush cleans a full arch in a single automated action of about 30 seconds per arch and incorporates pressure sensors for controlled force, soft bristles, antibacterial and biocompatible CE-certified materials, water resistance, and a battery lasting up to 14 days with wireless dock charging. The company states it is working to integrate advanced sensors for real-time oral-health monitoring, alongside a digital clinical record. The online store runs on a hosted e-commerce platform with common web analytics and tag-management tools.
Go-to-market
Customers buy the Smartbrush online, after which the company contacts them via WhatsApp to arrange a free intraoral scan at a partner dental clinic, or an alternative location where no nearby partner exists. The scan is used to assemble the personalised head configuration, which is then shipped to the customer's home together with the device. The offer includes free shipping, a two-year warranty and 24/7 customer service, and the site uses pre-order campaigns, promotional discounts tied to events such as World Oral Health Day, and a product-fit quiz. Distribution and credibility are anchored on the affiliated dentist network in Italy, supported by an SEO-oriented dental-health blog and social channels on Instagram, LinkedIn, YouTube and TikTok.
Adult consumers in Italy seeking a faster and more consistent daily oral hygiene routine, reached directly online and via partner dental clinics. The company states the device is not indicated for people under 18 or for adults with a range of dental, functional, systemic or neurological contraindications.
Geography
Headquartered in Milan, Italy, with a registered office at Via Privata del Gonfalone 3, 20123 Milan. Sales and the partner-clinic network for intraoral scanning are Italy-based. The company's stated roadmap targets expansion into France, Germany, the United Kingdom and the Nordic countries between Q2 2026 and Q4 2028, with entry into the United States planned after 2028.
History
The company was founded in 2024 and operates as Clean OS S.r.l., an Italian "startup innovativa" registered at Via Privata del Gonfalone 3, Milan, with a related entity Clean OS holding S.r.l. used for the equity crowdfunding offer. The plan presented during the campaign targeted an Italian launch of the Smartbrush in Q2/Q3 2025, European expansion between Q2 2026 and Q4 2028, and a US entry after 2028. By the time of the campaign the company reported partnerships with more than 40 Italian dental practices and a waiting list of prospective buyers; its website subsequently moved to pre-order and direct sales, with an editorial blog publishing dental-health articles through 2026.
Compiled by commissioned research from 8 cited public sources — announcements, filings, and press listed under research sources below.
Key figures
latest reportedCompany-reported or press-reported figures, each dated to when it was claimed — not independently audited.
Timeline · 2
launches, deals, and filingsClean OS holding S.r.l. ran an equity crowdfunding campaign on CrowdFundMe with a EUR 150,000 target and a EUR 600,000 maximum. The campaign closed overfunded at EUR 597,588 (398% of target) from 144 investors, corresponding to 16.6% of equity, at a stated pre-money valuation of EUR 2,997,603. Minimum investment was EUR 500 for class B shares carrying economic rights.
The company reports partnerships with 40+ Italian dental practices, including an affiliated network of 43 clinics offering discounted dental treatments to users and hosting the free intraoral scans.
Dated company events from announcements, filings, and press; legal rows summarize public dockets and regulator releases.
▸Research sources · 8
primary sources listed
- Clean OSthecleanos.com · web
8 public sources were cited for this profile; the first-party ones are listed here.
Frequently asked questions
- What does Clean OS do?
- Italian oral-care startup selling a full-arch electric toothbrush with brush heads custom-made from each user's intraoral scan.
- Who are Clean OS's investors?
- Clean OS's investors include Techstars.
- Where is Clean OS headquartered?
- Clean OS is headquartered in Milan, IT.

